Functional genomics screening

HTB supports automated screening of cells cultured in 96-, 384- or 1536-plate formats and can be applied to multiple investigator-initiated applications throughout the academic community.

The core maintains the -library and houses instruments needed to process a large amount of samples in high throughput fashion. Our platforms enable genome-wide, sub-library or candidate gene screens. We support both plate reader assays (luminescence, fluorescence, absorbance) and high content microscopy. We also provide expertise in assay development and optimization.

The Ambion Silencer® Select Human siRNA Library V4

The library is organized into three main groups: Druggable genome, the genome extension set, and the druggable genome extension set. The library consists of three individual siRNAs per target.

The library is available to be screened on 384-well plates

Custom library

We can also help you with designing and ordering custom siRNA or miRNA libraries. Please inquire.

How to get started?

All projects are customized to a researchers needs. A typical workflow for siRNA screening is shown here.

If you are interested in any of our services for application of your project, please complete the and we will contact you.