Chemical compound libraries

HTB maintains a collection of over 360 000 small molecule compounds including known drugs, bioactives, and diversified sets of chemicals.
Featured Compound Libraries

Explore some of the most popular chemical compound libraries from the HTB collection—featuring diverse molecules and focused sets designed to support cutting-edge drug discovery and phenotypic screening.

1. EU-Openscreen Diversity Collection

The EU-OPENSCREEN Compound Collection is a large, diverse screening library of over 100,000 small molecules contributed by academic and industrial partners across Europe. It enables high-quality, high-throughput screening and probe discovery for a wide range of biological targets. Researchers can also apply for and other European funding initiatives to access this library and integrate chemical biology screening into their projects.

2. FIMM Metabolic Library

The FIMM Metabolic Library (FB1C) is a focused collection of 183 small molecules targeting key metabolic pathways, including energy metabolism, lipid synthesis, and redox regulation. Designed to support studies on metabolic reprogramming in cancer and other diseases, the library enables systematic profiling of compound effects on cellular metabolism.

3. FIMM Oncology Library

The FIMM Oncology Library (FO6B) is a curated collection of 527 small molecules selected for their relevance to cancer biology and therapy. It includes both approved anticancer drugs and investigational agents targeting major oncogenic pathways, enabling comprehensive drug sensitivity testing, combination studies, and translational cancer research.