Assay development and optimization is often a bottleneck in drug discovery and chemical biology so we provide this support, both in terms of hands-on support as well as guidance and access to the best possible instrumentation and technologies.
Assay development starts by identifying the target and its activity. The next step is determining whether the objective is to inhibit or activate the target. A great starting point for assay development is a bench scale assay for the target used by the principal investigator, who initiates the small molecule screen by contacting the Drug Discovery, Chemical Biology and Screening platform. A small molecule chemical screen can be cell-based or based on a biochemical assay. The assay developers of the platform set up the assay and optimize it for high throughput screening.
If you want to initiate a new project at the FIMM High Throughput Biomedicine Unit or Faculty of Pharmacy and need support in assay development and optimization, please fill the contact form.
Contact form for services at the High Throughput Biomedicine unit
Contact form for services at the Faculty of Pharmacy