Faculty of Pharmacy
Faculty of Pharmacy provides a versatile selection of support for screening projects and follow-up studies:
- Expertise and support especially for antimicrobial screening, including host-pathogen co-cultures
- Antibacterial profiling for novel compounds
- Expertise on using natural products in screening
- Follow-up studies with organotypic cell models, cellular and vesicular drug transport assays and predictive pharmacokinetic models
- Computational ADME services, state-of-the-art predictions of pharmacokinetic properties, binding to metabolic proteins or transporters, and prediction of potential liabilities using statistical models developed in-house or available through commercial solutions.
- Expertise in database handling and machine-learning methods in particular deep-learning technologies
- Follow-up studies including virtual screening of compound collections using similarity searches, pharmacophore models and docking-based solutions
- LC/MS analytics for hits identified in in vitro screens and purity analyses of chemical libraries