Organelle protein targeting

Most of the proteins synthesized in the cytosol need to be relocated to the specific subcellular compartment, organelle, such as nucleus, endoplasmic reticulum, mitochondria, and peroxisomes. This requires well-established cellular protein logistics. Surprisingly little is known about the mechanisms and pathways by which proteins find their routes to the organelles.

Our research focuses on:

  • Mechanisms of tail-anchored protein targeting to peroxisomes
  • Identification and characterization of new peroxisomal biogenesis factors
  • Mechanisms of mitochondrial protein targeting

Svetlana Konovalova
Research Coordinator
Institute of Biotechnology, HiLIFE

Biocenter 2
P.O 56 (Viikinkaari 5)
00014 University of Helsinki

Phone: +358 29 41 59570