Each organelle has a very distinct structure depending on the functions it supports. Our aim is to understand structure-function interplay of organelles in mammalian cells. We employ a wide range of advanced imaging techniques, and have developed imaging software to analyze multidimensional imaging datasets.
Our main model organelle is the endoplasmic reticulum (ER). Many structural determinants of the ER network formation and maintenance have been described; however, it is not yet understood how the functional subdomains are formed and maintained, or how the ER is constantly rearranging. Our aim is to elucidate factors that generate and maintain the intricate balance of structure and dynamics underlying the functional efficacy of the ER.
Eija Jokitalo, PhD, Docent
Institute of Biotechnology, HiLIFE
Electron Microscopy unit, Biocenter 1
P.O. Box 56 (Viikinkaari 9C)
00014 University of Helsinki
Phone: +358 2941 59504, +358 50 469 6799
Eija is a Principal Investigator/Research Director at BI and the Director of BI Electron Microscopy Unit (EMBI). She is also the Chair of the Biocenter Finland Biological imaging platform (BF BioImaging).