Our body is constantly repaired and renewed by tissue-specific stem cells (aka. adult stem cells). In order to secure tissue homeostasis, generation of new stem cells via self-renewal and their differentiation into functional cells must be carefully balanced. As we age, the capacity of stem cells declines.
Our laboratory studies both stem cell-intrinsic and extrinsic mechanisms altering tissue renewal capacity, and how such mechanisms ultimately result in the functional decline we recognize as aging.
Our main focus areas are:
Pekka Katajisto, PhD, Professor
Director, Centre of Excellence in Stem Cell Metabolism
Institute of Biotechnology, HiLIFE & Faculty of Biological and Environmental Sciences
Biocenter 2, room 3018
P.O. Box 56 (Viikinkaari 5D)
00014 University of Helsinki
Office: +358 40 7085349
Pekka is a Principal Investigator/Group Leader at BI and Professor of Aging Biology at HiLIFE and Faculty of Biological and Environmental Sciences. He is the Director of the Center of Excellence in Stem Cell Metabolism (2018-2025) at the University of Helsinki. He also holds a position in Karolinska Institutet, Sweden, where he has a laboratory in the Department of Cell and Molecular Biology. Pekka was granted an ERC Starting Grant in 2015 and Consolidator Grant in 2022.