Publications

Selected and latest publications.
Selected publications
  1. Micoli G, Lavikka K, Li Y, Pirttikoski A, Afenteva D, Senkowski W, Marchi G, Vaharautio A, Muranen TA, Joutsiniemi T, Hietanen S, Virtanen A, Wennerberg K, Hynninen J, Oikkonen J, Hautaniemi S. Decoding the Genomic and Functional Landscape of Emerging Subtypes in Ovarian Cancer. Cancer Discovery. 2025 Jul 31.
  2. Afenteva D, Yu R, Rajavuori A, Salvadores M, Launonen IM, Lavikka K, Zhang K, Pirttikoski A, Marchi G, Jamalzadeh S, Isoviita VM, Li Y, Micoli G, Erkan EP, Falco MM, Ungureanu D, Lahtinen A, Oikkonen J, Hietanen S, Vähärautio A, Sur I, Virtanen A, Färkkilä A, Hynninen J, Muranen TA, Taipale J, Hautaniemi S. Multi-omics analysis reveals the attenuation of the interferon pathway as a driver of chemo-refractory ovarian cancer. Cell Reports Medicine. 2025 Aug 26:102316.
  3. Lahtinen A, Lavikka K, Virtanen A, Li Y, Jamalzadeh S, Skorda A, Lauridsen AR, Zhang K, Marchi G, Isoviita VM, Ariotta V, Lehtonen O, Muranen TA, Huhtinen K, Carpén O, Hietanen S, Senkowski W, Kallunki T, Häkkinen A, Hynninen J, Oikkonen J, Hautaniemi S. Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinoma. Cancer Cell. 2023 May 11:S1535-6108(23)00143-5.
  4. Lavikka K, Oikkonen J, Li Y, Muranen T, Micoli G, Marchi G, Lahtinen A, Huhtinen K, Lehtonen R, Hietanen S, Hynninen J, Virtanen A, Hautaniemi S. Deciphering cancer genomes with GenomeSpy: a grammar-based visualization toolkit. Gigascience. 2024 Jan 2;13:giae040.
  5. Zhang K, Erkan EP, Jamalzadeh S, Dai J, Andersson N, Kaipio K, Lamminen T, Mansuri N, Huhtinen K, Carpén O, Hietanen S, Oikkonen J, Hynninen J, Virtanen A, Häkkinen A, Hautaniemi S, Vähärautio A. Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer. Science Advances. 2022 Feb 25;8(8). 
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