FIMM Meta Publications

https://researchportal.helsinki.fi/en/equipments/fimm-metabolomics
  1. Taurine deficiency as a driver of aging., Singh P, Gollapalli K, Mangiola S, Schranner D, Yusuf MA, Chamoli M, Shi SL, Lopes Bastos B, Nair T, Riermeier A, Vayndorf EM, Wu JZ, Nilakhe A, Nguyen CQ, Muir M, Kiflezghi MG, Foulger A, Junker A, Devine J, Sharan K, Chinta SJ, Rajput S, Rane A, Baumert P, Schönfelder M, Iavarone F, di Lorenzo G, Kumari S, Gupta A, Sarkar R, Khyriem C, Chawla AS, Sharma A, Sarper N, Chattopadhyay N, Biswal BK, Settembre C, Nagarajan P, Targoff KL, Picard M, Gupta S, Velagapudi V, Papenfuss AT, Kaya A, Ferreira MG, Kennedy BK, Andersen JK, Lithgow GJ, Ali AM, Mukhopadhyay A, Palotie A, Kastenmüller G, Kaeberlein M, Wackerhage H, Pal B, Yadav VK., Science. 2023 Jun 9;380(6649):eabn9257. doi: 10.1126/science.abn9257. Epub 2023 Jun 9.
    PMID: 37289866
  2. Serum levels of carnosine may be associated with the duration of MDD episodes., Ali-Sisto T, Tolmunen T, Kraav SL, Mäntyselkä P, Valkonen-Korhonen M, Honkalampi K, Ruusunen A, Velagapudi V, Lehto SM., J Affect Disord. 2023 Jan 1;320:647-655. doi: 10.1016/j.jad.2022.09.092. Epub 2022 Oct 5.
    PMID: 36208690
  3. TNIK is a conserved regulator of glucose and lipid metabolism in obesity. Pham TCP, Dollet L, Ali MS, Raun SH, Møller LLV, Jafari A, Ditzel N, Andersen NR, Fritzen AM, Gerhart-Hines Z, Kiens B, Suomalainen A, Simpson SJ, Salling Olsen M, Kieser A, Schjerling P, Nieminen AI, Richter EA, Havula E, Sylow L  iScience 2023 Jan 20;26(1):105895. doi: 10.1016/j.isci.2022.105895, PMID: 36590899
  4. Clinical-Grade Patches as a Medium for Enrichment of Sweat-Extracellular Vesicles and Facilitating Their Metabolic Analysis. Rahat ST, Mäkelä M, Nasserinejad M, Ikäheimo TM, Hyrkäs-Palmu H, Valtonen RIP, Röning J, Sebert S, Nieminen AI, Ali N, Vainio S., Int J Mol Sci. 2023 Apr 19;24(8):7507. doi: 10.3390/ijms24087507.
  5. Pinto SM, Subbannayya Y, Kim H, Hagen L, Górna MW, Nieminen AI, Bjørås M, Espevik T, Kainov D, Kandasamy RK. MultiOMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells. iScience. 2022 Dec 28:105895. doi: 10.1016/j.isci.2022.105895. Online ahead of print. PMID: 36590899* 
  6. The red blood cell as a mediator of endothelial dysfunction in patients with familial hypercholesterolemia and dyslipidemia.Mahdi A, Wodaje T, Kövamees O, Tengbom J, Zhao A, Jiao T, Henricsson M, Yang J, Zhou Z, Nieminen AI, Levin M, Collado A, Brinck J, Pernow J. J Intern Med. 2023 Feb;293(2):228-245. doi: 10.1111/joim.13580. PMID: 36324273
  7. Inter-organellar and systemic responses to impaired mitochondrial matrix protein import in skeletal muscle. Neupane N, Rajendran J, Kvist J, Harjuhaahto S, Hu B, Kinnunen V, Yang Y, Nieminen AI, Tyynismaa H. Commun Biol. 2022 Oct 5;5(1):1060. doi: 10.1038/s42003-022-04034-z. PMID: 36198903
  8. Role of the cystathionine β-synthase / H2S pathway in the development of cellular metabolic dysfunction and pseudohypoxia in down syndrome. Panagaki T, Pecze L, Randi EB, Nieminen AI, Szabo C.Redox Biol. 2022 Jul 21;55:102416. PMID:35921774
  9. CRISPR correction of the Finnish ornithine delta-aminotransferase mutation restores metabolic homeostasis in iPSC from patients with gyrate atrophy. Maldonado R, Jalil S, Keskinen T, Nieminen AI, Hyvönen ME, Lapatto R, Wartiovaara K.Mol Genet Metab Rep. 2022 Apr 1;31:100863. PMID:35782600
  10. Machine Learning and Pathway Analysis-Based Discovery of Metabolomic Markers Relating to Chronic Pain Phenotypes. Miettinen T, Nieminen AI, Mäntyselkä P, Kalso E, Lötsch J.Int J Mol Sci. 2022 May 3;23(9):5085. PMID:35563473

  11. Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections. Ianevski A, Yao R, Zusinaite E, Lello LS, Wang S, Jo E, Yang J, Ravlo E, Wang W, Lysvand H, Løseth K, Oksenych V, Tenson T, Windisch MP, Poranen MM, Nieminen AI, Nordbø SA, Fenstad MH, Grødeland G, Aukrust P, Trøseid M, Kantele A, Lastauskienė E, Vitkauskienė A, Legrand N, Merits A, Bjørås M, Kainov DE., 2021,Viruses. 2021 Dec 11;13(12):2489.
  12. Cross-Laboratory Standardization of Preclinical Lipidomics Using Differential Mobility Spectrometry and Multiple Reaction Monitoring, Ghorasaini M, Mohammed Y, Adamski J, Bettcher L, Bowden JA, Cabruja M, Contrepois K, Ellenberger M, Gajera B, Haid M, Hornburg D, Hunter C, Jones CM, Klein T, Mayboroda O, Mirzaian M, Moaddel R, Ferrucci L, Lovett J, Nazir K, Pearson M, Ubhi BK, Raftery D, Riols F, Sayers R, Sijbrands EJG, Snyder MP, Su B, Velagapudi V, Williams KJ, de Rijke YB, Giera M. . Anal Chem. 2021 Dec 14;93(49):16369-16378. Epub 2021 Dec 3. PMID: 34859676
  13. One-carbon and energy metabolism in major depression compared to chronic depression in adolescent outpatients: A metabolomic pilot study. Kurkinen K, Kärkkäinen O, Lehto SM, Luoma I, Kraav S-L, Nieminen AI, Kivimäki P, Therman S, Tolmunen T, 2021, , Journal of Affective Disorders Reports, Dec 6: 100261 https://doi.org/10.1016/j.jadr.2021.100261
  14. Interactive effects of aging and aerobic capacity on energy metabolism-related metabolites of serum, skeletal muscle, and white adipose tissue, Zhuang H, Karvinen S, Törmäkangas T, Zhang X, Ojanen X, Velagapudi V, Alen M, Britton SL, Koch LG, Kainulainen H, Cheng S, Wiklund P. Geroscience. 2021 Dec;43(6):2679-2691. PMID:34089174
  15. Palviainen M, Laukkanen K, Tavukcuoglu Z, Velagapudi V, Kärkkäinen O, Hanhineva K, Auriola S, Ranki A, Siljander P. Cancer Alters the Metabolic Fingerprint of Extracellular Vesicles. Cancers (Basel). 2020 Nov 6;12(11):3292.  PMID:33172086
  16. Targeted Metabolomics With Ultraperformance Liquid Chromatography-Mass Spectrometry (UPLC-MS) Highlights Metabolic Differences in Healthy and Atopic Staffordshire Bull Terriers Fed Two Different Diets, Moore R, Anturaniemi J, Velagapudi V, Nandania J, Barrouin-Melo SM, Hielm-Björkman A. , A Pilot Study. Front Vet Sci. 2020 Oct 27;7:554296. PMID: 33195525
  17. Typhimurium impairs glycolysis-mediated acidification of phagosomes to evade macrophage defense., Gutiérrez S, Fischer J, Ganesan R, Hos NJ, Cildir G, Wolke M, Pessia A, Frommolt P, Desiderio V, Velagapudi V, Robinson N. Salmonella PLoS Pathog. 2021 Sep 23;17(9):e1009943. PMID: 34555129
  18. Hydroxysteroid (17β) dehydrogenase 12 is essential for metabolic homeostasis in adult mice, Heikelä H, Ruohonen ST, Adam M, Viitanen R, Liljenbäck H, Eskola O, Gabriel M, Mairinoja L, Pessia A, Velagapudi V, Roivainen A, Zhang FP, Strauss L, Poutanen M. . Am J Physiol Endocrinol Metab. 2020 Sep 1;319(3):E494-E508. PMID: 32691632
  19. IMPDH2: a new gene associated with dominant juvenile-onset dystonia-tremor disorder, Kuukasjärvi A, Landoni JC, Kaukonen J, Juhakoski M, Auranen M, Torkkeli T, Velagapudi V, Suomalainen A. Eur J Hum Genet. 2021 Dec;29(12):1833-1837. doi: 10.1038/s41431-021-00939-1. Epub 2021 Jul 26. PMID: 34305140
  20. Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy, Pirinen E, Auranen M, Khan NA, Brilhante V, Urho N, Pessia A, Hakkarainen A, Ulla Heinonen JK, Schmidt MS, Haimilahti K, Piirilä P, Lundbom N, Taskinen MR, Brenner C, Velagapudi V, Pietiläinen KH, Suomalainen A. . Cell Metab. 2020 Jul 7;32(1):144. doi: 10.1016/j.cmet.2020.05.020. Erratum for: Cell Metab. 2020 Jun 2;31(6):1078-1090.e5. PMID: 32640244.
  21. Over the Left Prefrontal Cortex Does Not Cause Clinically Significant Changes in Circulating Metabolites, Kortteenniemi A, Ortega-Alonso A, Javadi AH, Tolmunen T, Ali-Sisto T, Kotilainen T, Wikgren J, Karhunen L, Velagapudi V, Lehto SM. Anodal tDCS . Front Psychiatry. 2020 May 7;11:403. doi: 10.3389/fpsyt.2020.00403. PMID: 32458831
  22. Simultaneous Measurement of Tricarboxylic Acid Cycle Intermediates in Different Biological Matrices Using Liquid Chromatography–Tandem Mass Spectrometry; Quantitation and Comparison of TCA Cycle Intermediates in Human Serum, Plasma, Kasumi-1 Cell and Murine Liver Tissue. Rathod, R.; Gajera, B.; Nazir, K.; Wallenius, J.; Velagapudi, V.  Metabolites 2020, 10, 103. https://doi.org/10.3390/metabo10030103.
  23. Disruption of the mouse Shmt2 gene confers embryonic anaemia via foetal liver-specific metabolomic disorders. Sci Rep 9, 16054 (2019). Haruna T, Takayuki M, Vidya V, Kaori I, Moe U, Kazuto N, Anu S & Jun-Ichi H. https://doi.org/10.1038/s41598-019-52372-6.
  24. Repeated Transcranial Magnetic Stimulation-Induced Motor Evoked Potentials Correlate With the Subject-Specific Serum Metabolic Profile of Creatine. J Clin Neurophysiol. 2019.Kallioniemi E, Kärkkäinen O, Määttä S, Könönen M, Kivimäki P, Kaarre O, Velagapudi V, Kekkonen V, Lehto SM, Laukkanen E, Tolmunen T. PMID:30720554
  25. Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci. Clin Epigenetics. 2019 Jan 5;11(1):1.Gupta R, van Dongen J, Fu Y, Abdellaoui A, Tyndale RF, Velagapudi V, Boomsma DI, Korhonen T, Kaprio J, Loukola A, Ollikainen M. PMID:30611298 
  26. Changes in the serum metabolite profile correlate with decreased brain grey matter volume in heavy-drinking young adults. Alcohol. 2019; 75:89-97. Heikkinen, N., Kärkkäinen, O., Laukkanen, E., Kekkonen, V., Kaarre, O., Kivimäki, P., Könönen, M., Velagapudi, V.Nandania, J., Lehto, S., Niskanen, E., Vanninen, R., Tolmunen, T. PMID:30513444
  27. Metabolomes of mitochondrial diseases and inclusion body myositis: treatment targets and biomarkers. EMBO Molecular Medicine. 2018  Dec;10(12).Buzkova, J., Nikkanen, J., Ahola, S., Hakonen, A., Sevastianova, K., Hovinen, T., Yki-Järvinen, H., Pietiläinen, K., Lönnqvist, T., Velagapudi, V., Carroll, C., Suomalainen, A.  PMID:30373890
  28. A Systems Approach to Study Immuno- and Neuro-Modulatory Properties of Antiviral Agents. Viruses. 2018 Aug 12;10(8).Zusinaite E, Ianevski A, Niukkanen D, Poranen MM, Bjørås M, Afset JE, Tenson T, Velagapudi V, Merits A, Kainov DE. PMID:30103549
  29. Simultaneous measurement of folate cycle metabolites using liquid chromatography-tandem mass spectrometry from different biological matrices. Journal of Chromatography B. 2018; 15:1092: 168-178.Nandania, J., Kokkonen, M., Euro, L, Velagapudi, V.  PMID:29906678
  30. Adipose tissue mitochondrial gene expression profile associates with long-term weight loss success. International Journal of Obesity. 2018; 42;817–825. Jokinen, R., Rinnankoski-Tuikka, R., Kaye, S., Saarinen, L., Heinonen, S., Myöhänen, M., Rappou, E., Jukarainen, S., Kaprio, J., Rissanen, A., Pessia, A., Velagapudi, V., Virtanen, K., Pirinen, E and Pietiläinen, K. PMID:29203860
  31. Validation and automation of high-throughput multi-targeted method for semi-quantification of endogenous metabolites from different biological matrices using tandem mass spectrometry. Metabolites. 2018; 5:8:3. Nandania, J., Peddinti, G., Pessia, A., Kokkonen, M., Velagapudi, V. PMID:30081599
  32. Pre-analytical Processing and Biobanking Procedures of Biological Samples for Metabolomics Research: A White Paper, Community Perspective (for “Precision Medicine and Pharmacometabolomics Task Group” – The Metabolomics Society Initiative). Clinical Chemistry. 2018; 64:8:1158-1182. Kirwan, J., Brennan, L., Broadhurst, D., Fiehn, O., Cascante, M., Dunn, W., Schmidt, M., Velagapudi, V.  PMID:29921725
  33. Plasma metabolites reveal distinct profiles associating with different metabolic risk factors in monozygotic twin pairs. International Journal of Obesity. 2018;Muniandy, M., Velagapudi, V., Hakkarainen, A., Lundbom, J., Lundbom, N., Rissanen, A., Kaprio, J., Pietiläinen, K., Ollikainen, M. PMID:29907843
  34. Understanding the metabolic burden of recombinant antibody production in Saccharomyces cerevisiae using a quantitative metabolomics approach. Yeast. 2018; 35(4):331-341. De Ruijter, J., Koskela, E., Nandania, J., Frey, A., Velagapudi, V. PMID: 29159981
  35. Global arginine bioavailability ratio is decreased in patients with major depressive disorder. Journal of Affective Disorders. 2018; 15;229:145. Ali-Sisto, T., Tolmunen, T., Toffol, E., Viinamäki, H., Mäntyselkä, P., Valkonen-Korhonen, M., Honkalampi, K., Ruusunen, A., Velagapudi, V., Lehto, S.M. PMID:29310063
  36. Host-Microbe Co-metabolism Dictates Cancer Drug Efficacy in C.elegans. Cell. Scott TA, Quintaneiro LM, Norvaisas P, Lui PP, Wilson MP, Leung KY, Herrera-Dominguez L, Sudiwala S, Pessia A, Clayton PT, Bryson K, Velagapudi V, Mills PB, Typas A, Greene NDE, Cabreiro F. (2017). PMID:2843124
  37. Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins.  Viruses. 2017; 9, 271. Bulanova, D., Ianevski, A., Bugai, A., Akimov, Y., Kuivanen, S., Paavilainen, H., Kakkola, L., Nandania, J., Turunen, L., Ohman, T., Ala-Hongisto, H., Pesonen, H.M., Kuisma, M.S., Honkimaa, A., Walton, E.L., Oksenych, V., Lorey, M.B., Guschin, D., Shim, J., Kim, J., Than, T.T., Chang, S.Y., Hukkanen, V., Kulesskiy, E., Marjomaki, V.S., Julkunen, I., Nyman, T.A., Matikainen, S., Saarela, J.S., Sane, F., Hober, D., Gabriel, G., De Brabander, J.K., Martikainen, M., Windisch, M.P., Min, J.Y., Bruzzone, R., Aittokallio, T., Vähä-Koskela, M., Vapalahti, O., Pulk, A., Velagapudi, V., Kainov, D.E. PMID:28946654
  38. mTORC1 Regulates Mitochondrial Folate Cycle and the Integrated Stress Response in Mitochondrial Disease. Cell Metabolism. 2017; 26(2):419-428. Khan, N.A., Nikkanen, J., Yatsuga, S., Wang, L., Jackson, C., Pessia, A., Riikka Kivelä, Velagapudi, V., Anu Suomalainen. PMID:28768179
  39. Metabolomic profiling of extracellular vesicles and alternative normalisation methodsreveal enriched metabolites and strategies to study prostate cancer related changes. Puhka, M., Takatalo, M., Nordberg, M.E., Valkonen, S., Nandania, J., Aatonen, M., Yliperttula, M., Laitinen, S., Velgapudi, V., Mirtti, T., Kallioniemi, O., Rannikko, A., Siljander, P.R.M., af Hallstrom, T.M. Theranostics. 2017; 7(16): 3824-3841. 
  40. Ketogenic diet attenuates hepatopathy in mouse model of respiratory chain complex III deficiency caused by a Bcs1l mutation. Scientific Reports. Purhonen, J., Rajendran, J., Mörgelin, M., Uusi-Rauva, K., Katayama, S., Krjutskov, K., Einarsdottir, E., Velagapudi, V., Kere, J., Jauhiainen, M., Fellman, V., Kallijärvi, J. (2017). PMID:28424480
  41. Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics. The FASEB Journal. Vorrink, S..U., Ullah, S., Schmidt, S., Nandania, J., Velagapudi, V., Beck, O., Ingelman-Sundberg, M., Lauschke, V.M. (2017). PMID:28264975
  42. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs.  Journal of Cell Biology. Schatton, D., Pla-Martin, D., Marx, M.C., Hansen, H., Mourier, A., Nemazanyy, I., Pessia, A., Zentis, P., Corona, T. Kondylis, V., Barth, E., Schauss, A.C., Velagapudi, V., Rugarli, E. (2017).PMID:28188211
  43. Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology. Disease Models and Mechanisms. Szibor, M., Dhandapani, PK., Dufour, E., Holmström, KM., Zhuang, Y., Salwig, I., Wittig, I., Heidler, J., Gizatullina, Z., Gainutdinov, T., Consortium, GM., Fuchs, H., Gailus-Durner, V., de Angelis, MH., Nandania, J., Velagapudi, V., Wietelmann, A., Rustin, P., Gellerich, FN., Jacobs, HT., Braun, T. (2017). PMID:28067626
  44. Obatoclax, saliphenylhalamide and gemcitabine inhibit Zika virus infection in vitro and differentially affect cellular signaling, transcription and metabolism. Antiviral Research. Kuivanen, S., Bespalov, MM., Nandania, J., Ianevski, A., Velagapudi, V., De Brabander, JK., Kainov, DE., Vapalahti, O. (2017). PMID:28049006.
  45. Regulation of Kynurenine Biosynthesis during Influenza Virus Infection. The FEBS Journal. Gaelings, L., Söderholm, S., Bugai, A., Fu, Y., Nandania, J., Schepens, B., Lorey, M.B., Tynell, J., Ginste, L.S., Goffic, R.L., Miller, M.S., Kuisma, M., Marjomäki, V., Brabander, J.D., Matikainen, S., Nyman, T.A., Bamford, D., Saelens, X., Julkunen, I., Paavilainen, H., Hukkanen, V., Velagapudi, V., Kainov, D.E. (2017).PMID:27860276
  46. The association between musculoskeletal pain and circulating ornithine – A population-based study. Pain Medicine. Mäntyselkä, P., Ali-Sisto, T., Kautiainen, H., Savolainen, J., Niskanen, L., Viinamäki, H., Velagapudi, V., Lehto, S.M. (2016).PMID:28034972
  47. Combined immunodeficiency with hypoglycemia caused by mutations in hypoxia up-regulated 1The Journal of Allergy and Clinical Immunology. Haapaniemi, E., Fogarty, C., Katayama, S., Vihinen, H., Keskitalo, S., Ilander, M., Krjutškov, K., Mustjoki, S., Lehto, M., Hautala, T., Jokitalo, E., Velagapudi, V., Varjosalo, M., Seppänen, M., Kere, J. (2016). PMID:27913302
  48. Effect of high-carbohydrate diet on plasma metabolomics in mice with mitochondrial respiratory chain complex III deficiency due to a Bcs1l mutation. International Journal of Molecular Sciences. Rajendran, J., Tomašić, N., Kotarsky, H., Hansson, E., Velagapudi, V., Kallijärvi, J., Fellman, V. (2016). PMID:27809283
  49. Activation of Tryptophan and Phenylalanine Catabolism in the Remission Phase of Allergic Contact Dermatitis: A Pilot Study. International Archives of Allergy and Immunology. Zinkevičienė A, Kainov D, Girkontaitė I, Lastauskienė E, Kvedarienė V, Fu Y, Anders S, Velagapudi V. (2016). PMID: 27771694
  50. Fecal and serum metabolomics in pediatric inflammatory bowel disease. Journal of Crohn’s and ColitisKolho, K-L., Pessia, A., Jaakkola, T., de Vos, W., Velagapudi, V. (2016).  PMID: 27609529
  51. Modified Atkins diet induces subacute selective ragged red fiber lysis in mitochondrial myopathy patients. EMBO Molecular Medicine. Ahola, S., Auranen, M., Isohanni, P., Niemisalo, S., Buzkova, J., Velagapudi, V., Lundbom, N., Hakkarainen, A., Piirilä, P., Pietiläinen, K., Suomalainen, A. (2016).  PMID: 27647878 Press release
  52. The Pentose Phosphate Pathway Regulates the Circadian Clock. (2016). Cell Metabolsim.  Rey, G., Valekunja, U.K., Feeney, K.A., Wulund, L., Milev, N.B., Stangherlin, A., Bollepalli, L., Velagapudi, V., O’Neill, J.S., Reddy, A.B.PMID: 27546460
  53. JNJ872 inhibits influenza A virus replication without altering cellular antiviral responses. Antiviral Research.  Fu Y, Gaelings L, Söderholm S, Belanov S, Nandania J, Nyman TA, Matikainen S, Anders S, Velagapudi V, Kainov DE. (2016). PMID: 27451344
  54. GATA4 regulates blood-testis barrier function and lactate metabolism in mouse Sertoli cells. Endocriniology. Schrade, A., Kyrönlahti, A., Akinrinade, O., Pihlajoki, M., Fischer, S., Martinez Rodriguez, V., Velagapudi V, Toppari, J., Wilson, DB., Heikinheimo, M. (2016). PMID: 26974005
  55. Purine metabolism is dysregulated in patients with major depressive disorder. Psychoneuroendocrinology. Ali-Sisto, T., Tolmunen, T., Toffol, E., Viinamäki, H., Mäntyselkä, P., Valkonen-Korhonen, M., Honkalampi, K., Ruusunen, A., Velagapudi V, Lehto, S.M. (2016). MID: 27153521
  56. Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools And Remodel One-Carbon Metabolism. Cell Metabolism. Nikkanen J, Forsström S, Euro L, Paetau I, Kohnz R.A, Wang L, Chilov D, Viinamäki J, Roivainen A, Marjamäki P, Liljenbäck H, Ahola S, Buzkova J, Terzioglu M, Khan N.A, Pirnes-Karhu S, Paetau A, Lönnqvist T, Sajantila A, Isohanni P, Tyynismaa H, Nomura D.K, Battersby B, Velagapudi V, Carroll C.J, Suomalainen A. (2016). PMID: 26924217
  57. GATA4 is a key regulator of steroidogenesis and glycolysis in mouse Leydig cells. Endocrinology. Schrade A, Kyrönlahti A, Akinrinade O, Pihlajoki M, Häkkinen M, Fischer S, Alastalo T.P, Velagapudi V, Toppari J, Wilson D.B, Heikinheimo M (2015). PMID: 25668067
  58. Vitamin B12–dependent taurine synthesis regulates growth and bone mass. Journal of Clinical Investigation. Roman-Garcia P, Quiros-Gonzalez I, Mottram L, Lieben L, Sharan K, Wangwiwatsin A, Tubio J, Lewis K, Wilkinson D, Santhanam B, Sarper N, Clare S, Vassiliou GS, Velagapudi V, Dougan G, Yadav V.K. (2014).PMID: 24911144
  59. Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3. EMBO Molecular Medicine. Khan N.A, Auranen M, Paetau I, Pirinen E, Euro L, Forsström S, Pasila L, Velagapudi V, Carroll C.J, Auwerx J, Suomalainen A. (2014). PMID: 24711540