Stem Cells and Metabolism Research Program (STEMM) brings together eleven research groups and four associated clinical researchers interested in cellular metabolism as a driving force in tissue homeostasis, cellular differentiation and degenerative diseases. Many of the groups take advantage of the possibilities of stem cell and genome editing technologies to understand molecular disease mechanisms in order to develop innovative treatments. Close ties to pediatric and neurology clinics enable efficient use of our research findings for diagnosis, patient care and counselling.
- Elina Ikonen - Lipid Trafficking Lab
- Jukka Kallijärvi - Mechanisms and Therapies of Mitochondrial CIII Deficiencies
- Juha Kere - Genetics of Complex Phenotypes
- Riikka Kivelä - Endothelial and Stem Cells Regulating Tissue Function
- Satu Kuure - Kidney Development
- Thomas McWilliams - Mitochondrial Homeostasis in Development, Disease & Repair
- Taneli Raivio - Genetics and Disease Modeling with Human Pluripotent Stem Cells
- Anu Suomalainen-Wartiovaara - Mitochondrial Medicine
- Henna Tyynismaa - Medical Neurogenetics
- Sara Wickström - Stem Cells and Tissue Architecture
Associated Clinical Researchers
- Emmi Helle
- Pirjo Isohanni
- Risto Lapatto
- Kirmo Wartiovaara
- Emil Ylikallio
New Publications from STEMM
- McWilliams TG, Suomalainen A. Mitochondrial DNA can be inherited from fathers, not just mothers. Nature. Jan 2019 .
- Miroshnikova YA, Hammesfahr T, Wickström SA: Cell biology and mechanopathology of laminopathic cardiomyopathies. J Cell Biol. Jan 10, 2019.
Varimo T, Huopio H, Kariola L, Tenhola S, Voutilainen R, Toppari J, Toiviainen-Salo S, Hämäläinen E, Pulkkinen M-A, Lääperi M, Tarkkanen A, Vaaralahti K, Miettinen PJ, Hero M, Raivio T: Letrozole versus testosterone for promotion of endogenous puberty in boys with constitutional delay of growth and puberty: a randomised controlled phase 3 trial. Lancet Child Adolesc Health. Jan 3, 2019.