8:30 - 9:00 Registration
9:00 - 9:20 Opening of the meeting
9:20 - 10:00 Frank Kooy, University of Antwerp, Belgium: Clinical development of targeted treatments for fragile X syndrome
10:00 - 10:30 Coffee break
10:30 - 11:10 Ilario de Toma, Barcelona Institute of Science and Technology, Spain: A transcriptomic approach to conceive new therapies for Down syndrome and its comorbidities
11:10 - 11:50 Yolanda de Diego Otero, Malaga, Spain: Antioxidants in clinical trials for fragile X syndrome
11:50 - 12:20 Presentation of family association for Down syndrome/fragile X syndrome
12:20 - 14:00 Lunch
14:00 - 14:40 Pierre Gressens, INSERM, Université Paris Diderot, Paris, France: Developmental background of neurodevelopmental disorders; potential clinical targets
14:40 - 15:00 Samuel Chawner, Cardiff University, UK: A genomics first approach to understanding neurodevelopmental disorders: deep phenotyping of copy number variant carriers
15:00 - 15:40 Mark Daly, FIMM, University of Helsinki, Finland: Genetics of neurodevelopmental disorders
15:40 - 16:10 Coffee break
16:10 - 16:50 Jari Koistinaho, University of Helsinki, Finland: Transcriptomic and proteomic signatures of patient-specific neuronal cells in schizophrenia and psychopathy
16:50 - 17:10 Justin Chung, University of Birmingham, UK: The development and evaluation of the Emotional Outburst Questionnaire
17:10 - 17.30 Francesco Bedogni, San Raffaele Hospital, Milan, Italy: Enhancement of activity rescues the early establishment of Mecp2 null neuronal features
17:30 - 17: 45 Maija Castrén: Summary of the first day
17:45 - 18:30 Poster session
19:00 - 20:00 City of Helsinki Welcome Reception
The City of Helsinki invites the participants of the Workshop to the City Reception in the Empire Room of the Old Town Hall on Thursday, 15th August at 19:00-20:00.
The Old Town Hall is located next to the Senate Square (Alexanterinkatu 20) surrounded by the Helsinki Cathedral, the Government Palace, and the main building of the University of Helsinki in the Empire-style old city centre. Merchant Bock´s house served as the residence of the governor-generals in the Russian era and was turned into town hall in 1838. Excluding its ground floor offices, the Old Town Hall currently serves City´s receptions.
Please note that it might not be possible to register to the City Reception on-site.
Find the Helsinki City Hall on Google Maps
9:15 - 9:55 Barbara Bardoni, Inserm, France: Inhibition of PDE2A as therapeutic target for fragile X syndrome and autism spectrum disorders
9:55 - 10:15 Susanna Narkilahti, Tampere University, Finland: Microarrays for identification of defective connectivity in brain diseases
10:15-10:45 Coffee break
10:45-11:25 Mahmoud Pouladi, University of Singapore, Singapore: Mechanisms disturbed in triplet repeat diseases
11:25-11:55 Maija Castrén, University of Helsinki, Finland: Human stem cells modelling neurodevelopmental diseases
11:55 – 12:15 Svetlana Molchanova, University of Helsinki, Finland: Alpha2-containing glycine receptors promote neonatal activity of striatal projection neurons and support excitatory synapse maturation
12:30 - 13:30 Lunch
13:30 -14:10 Andreas Frick, Inserm, France: Calcium signalling changes in autism spectrum disorders
14:10 - 14:50 Laurent Roybon replaced by Eero Castrén, Neuroscience Center, University of Helsinki, Finland: Activation of neurotrophin receptor TrkB in interneurons orchestrates cortical plasticity
14:50 - 15:30 Mikko Airavaara, Neuroscience Center, University of Helsinki, Finland: Role of ER homeostasis in cortex development
15:30 - 16:00 Coffee break
16:00 - 16:40 Claudio Rivera, Inserm, Marseille/University of Helsinki, Finland: Chloride transporters in brain diseases
16:40 - 17:20 Juha Salmitaival, University of Helsinki, Finland: Brain imaging of network dysfunction in autism
17:20 -17:30 Closing of the meeting