Programme

Abstraktit

 

Thursday 15.8.2019

8:30 - 9:00      Registration
9:00 - 9:20      Opening of the meeting

9:20 - 10:00    Frank Kooy, University of Antwerp, Belgium: Clinical development of targeted treatments for fragile X syndrome
      
10:00 - 10:30  Coffee break

10:30 - 11:10   Ilario de Toma, Barcelona Institute of Science and Technology, Spain: A transcriptomic approach to conceive new therapies for Down syndrome and its comorbidities

11:10 - 11:50   Yolanda de Diego Otero, Malaga, Spain: Antioxidants in clinical trials for fragile X syndrome

11:50 - 12:20   Presentation of family association for Down syndrome/fragile X syndrome

12:20 - 14:00  Lunch

14:00 - 14:40  Pierre Gressens, INSERM, Université Paris Diderot, Paris, France: Developmental background of neurodevelopmental disorders; potential clinical targets

14:40 - 15:00  Samuel Chawner, Cardiff University, UK: A genomics first approach to understanding neurodevelopmental disorders: deep phenotyping of copy number variant carriers

15:00 - 15:40    Mark Daly, FIMM, University of Helsinki, Finland: Genetics of neurodevelopmental disorders

15:40 - 16:10  Coffee break

16:10 - 16:50  Jari Koistinaho, University of Helsinki, Finland: Transcriptomic and proteomic signatures of patient-specific neuronal cells in schizophrenia and psychopathy

16:50 - 17:10 Justin Chung, University of Birmingham, UK: The development and evaluation of the Emotional Outburst Questionnaire

17:10 - 17.30 Francesco Bedogni, San Raffaele Hospital, Milan, Italy: Enhancement of activity rescues the early establishment of Mecp2 null neuronal features

17:30 - 17: 45 Maija Castrén: Summary of the first day

17:45 - 18:30  Poster session

19:00 - 20:00  City of Helsinki Welcome Reception

The City of Helsinki invites the participants of the Workshop to the City Reception in the Empire Room of the Old Town Hall on Thursday, 15th August at 19:00-20:00.

The Old Town Hall is located next to the Senate Square (Alexanterinkatu 20) surrounded by the Helsinki Cathedral, the Government Palace, and the main building of the University of Helsinki in the Empire-style old city centre. Merchant Bock´s house served as the residence of the governor-generals in the Russian era and was turned into town hall in 1838. Excluding its ground floor offices, the Old Town Hall currently serves City´s receptions.

Please note that it might not be possible to register to the City Reception on-site.

Find the Helsinki City Hall on Google Maps

16.8.2019

9:15 - 9:55       Barbara Bardoni, Inserm, France: Inhibition of PDE2A as therapeutic target for fragile X syndrome and autism spectrum disorders

9:55 - 10:15      Susanna Narkilahti, Tampere University, Finland: Microarrays for identification of defective connectivity in brain diseases

10:15-10:45    Coffee break

10:45-11:25    Mahmoud Pouladi, University of Singapore, Singapore: Mechanisms disturbed in triplet repeat diseases

11:25-11:55   Maija Castrén, University of Helsinki, Finland: Human stem cells modelling neurodevelopmental diseases

11:55 – 12:15  Svetlana Molchanova, University of Helsinki, Finland: Alpha2-containing glycine receptors promote neonatal activity of striatal projection neurons and support excitatory synapse maturation

12:30 - 13:30    Lunch

13:30 -14:10    Andreas Frick, Inserm, France: Calcium signalling changes in autism spectrum disorders

14:10 - 14:50    Laurent Roybon replaced by Eero Castrén, Neuroscience Center, University of Helsinki, Finland: Activation of neurotrophin receptor TrkB in interneurons orchestrates cortical plasticity 

14:50 - 15:30   Mikko Airavaara, Neuroscience Center, University of Helsinki, Finland: Role of ER homeostasis in cortex development

15:30 - 16:00     Coffee break

16:00 - 16:40      Claudio Rivera, Inserm, Marseille/University of Helsinki, Finland: Chloride transporters in brain diseases

16:40 - 17:20       Juha Salmitaival, University of Helsinki, Finland: Brain imaging of network dysfunction in autism

17:20 -17:30      Closing of the meeting