We offer the following genome profiling services at the FIMM Genomics. Below you can find short description of our services. Complete information about ordering and contacts are found in
Services routinely provided by FIMM Genomics include DNA sequencing (exome, whole-genome, ready-made and custom gene panels) using a number of different library preparations systems and NovaSeq X Plus, MiSeq, or AVITI24 instrumentation. Sequencing read length ranges from 36 to over 300 bases depending on the instrument. The service includes sample QC, library preparation, sequencing, data pre-processing and analysis if requested by the customer.
FIMM Genomics provides a wide variety of RNA-seq services (e.g. whole transcriptome, 3' counting, smallRNA) using Illumina and AVITI sequencing instrumentation (NovaSeq X Plus, AVITI24 and MiSeq). Transcriptome analysis includes nucleic acid QC, library preparation and sequencing. Downstream data analysis is offered using a number of different options depending on the application.
NanoString nCounter assays can be applied for targeted mRNA, miRNA and protein expression analyses. The technology is based on direct hybridization of target-specific color-coded probes and therefore, no cDNA synthesis or amplification of RNA is required. Starting material can originate from FFPE samples, tissue, cells, or plasma.
This service has been set-up in 2015 and it is based on detecting specific protein expression by antibodies that are linked with oligos. Each protein is detected by two antibodies, which are linked with complementary oligos. Binding of the oligos can be detected and protein expression from up to 90 proteins from up to 92 samples is quantified using qPCR or up to 1,000 proteins using NGS as a readout.
We provide computational analyses for next-generation sequencing. The analysis services are categorized into basic and advanced data analysis according to the scope and objectives of the study.