Skip to main content

Mitochondrial homeostasis in development, disease & repair

Menu
FlammaCity of Helsinki
  • en
  • fi
  • sv
  • Home
  • RESEARCH
  • POSITIONS
  • TEAM
  • Publications
  • RESEARCH
  • POSITIONS
  • TEAM
  • Publications

Mitochondrial homeostasis in development, disease & repair

McWilliams Lab

Mitochondrial homeostasis in development, disease & repair research group

Welcome to the McWilliams Lab @ University of Helsinki

The McWilliams lab is driven to understand the striking heterogeneity of tissue-specific autophagy signalling in mammalian health and disease. We have a particular interest in how autophagy regulates mitochondrial integrity in vivo, with an integrative approach that combines molecular mechanistic discovery in cell-based models with rigorously deciphering the physiological significance of our observations in transgenic and pre-clinical models. Our research is highly multidisciplinary, and we combine a plethora of approaches in molecular cell biology with sophisticated transgenic strategies, gene editing and advanced methods in biomedical imaging. We benefit greatly from the well-resourced and outstanding platforms in Helsinki, with in-house expertise in single cell transcriptomics, metabolomics, genome editing, organoid approaches, state-of-the-art in vivo imaging and electron microscopy. Being embedded within one of Europe's leading medical campuses, we enjoy close collaborative links with exceptional clinical researchers and scientists who partner with us in our quest to make a meaningful impact at the interface between discovery and translation.
Click to read about what we do.

Main topics

Publications
TestikuvaMcWilliams

Research

We aim to unravel the regulation of mitochondrial homeostasis in health and disease. Mitochondrial signalling: a matter of life and...
KuvituskuvaMcWilliams

POSITIONS

We are al­ways in­ter­ested in hear­ing from en­thu­si­astic post-doc­toral sci­ent­ists and stu­dents. Often cited as the land of a...
TomMcWilliams

TEAM

  McWilliams Lab

News

Research
Parkinson's disease
7.11.2018
Health news

A molecular switch links a Scottish mouse, a Finnish patient and Parkinson’s disease

Researchers at the Faculty of Medicine, University of Helsinki, make an unexpected and vital contribution to an international collaborative...
Researcher Thomas McWilliams, PhD, Assistant Professor
25.5.2018
Health news

“There has never been a better time to be a mitochondriac!”

Mitochondrial research is undergoing a renaissance in the field of biomedicine, says Assistant Professor Thomas McWilliams. No wonder, since...

Tom McWilliams joins Molecular Neurology Research Program

Tom McWilliams appointed Assistant Professor of Mitochondrial Medicine & Academy Scientist at University of Helsinki
@tom_mcneuro
Follow
22.02.2019
Marjukka Myllärniemi
@myllarni

Great group looking for reinforcement @helsinkiuni twitter.com/tom_mcneuro/st…

Favorites 3
Retweets 3
22.02.2019
Ville Paavilainen
@v_paavilainen

@tom_mcneuro @fumi_suomi @kirsi_mattinen @amchelsinki @STEMMProgram @helsinkiuni Great lab! @tom_mcneuro beautiful… twitter.com/i/web/status/1…

Favorites 2
Retweets 1

Funding

Updated: 9.10.2018

Up
University of Helsinki

P.O. Box 3
(Fabianinkatu 33)
00014 University of Helsinki

Switchboard:
+358 (0) 2941 911

People finder and contacts Press and MediaWorking at the UniversityLibrary Flamma
About the Website Data Protection Give Feedback

© University of Helsinki 2019