Publications

SELECTED RECENT PUBLICATIONS

*Co-Corresponding Author

ALL PUBLICATIONS

2019

Suomi F, McWilliams TG. Autophagy in the mammalian nervous system: a primer for neuroscientists. Neuronal Signaling 3: NS20180134, 2019. Article selected for Journal Cover Image

Muha V, Williamson R, Hills R, McNeilly AD, McWilliams TG, Alonso J, Schimpl M, Leney AC, Heck AJR, Sutherland C, Read KD, McCrimmon RJ, Brooks SP, van Aalten DMF. Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice. Open Biol 9: 190192, 2019. 

Howard L, McWilliams TG, Wyatt S, Davies AM. CD40 forward signalling is a physiological regulator of early sensory axon growth. Development 146: dev176495, 2019.

Long M, McWilliams TG. Monitoring autophagy in cancer: From bench to bedside. Semin Cancer Biol in press, 2019.

McWilliams TG, Prescott AR, Villarejo-Zori B, Ball G, Boya P, Ganley IG. A comparative map of macroautophagy and mitophagy in the vertebrate eye. Autophagy 15: 1296-1308, 2019.

McWilliams TG*, Suomalainen A*. Mitochondrial DNA can be inherited from fathers, not just mothers. Nature 565: 296-297, 2019.

McWilliams TG, Ganley IG. Investigating mitophagy and mitochondrial morphology in vivo using mito-QC: a comprehensive guide. Methods Mol Biol 1880: 621-642, 2019.

Singh F, Zoll J, Duthaler U, Charles AL, Panajatovic MV, Laverny G, McWilliams TG, Metzger D, Geny B, Krähenbühl S, Bouitbir J. PGC-1β modulates statin-associated myotoxicity in mice. Arch Toxicol 93: 487-504, 2019.

2018

McWilliams TG*, Barini E, Pohjolan-Pirhonen R, Brooks SP, Singh F, Burel S, Balk K, Kumar S, Montava-Garriga L, Prescott AR, Hassoun SM, Mouton-Liger F, Ball G, Hills R, Knebel A, Ulusoy A, Di Monte DA, Tamjar J, Antico O, Fears K, Smith L, Brambilla R, Palin E, Valori M, Eerola-Rautio J, Tienari P, Corti O, Dunnett SB, Ganley IG, Suomalainen A, Muqit MMK*. Phosphorylation of Parkin at serine 65 is essential for its activation in vivoOpen Biol 8: 180108, 2018.

McWilliams TG*, Prescott AR, Montava-Garriga L, Ball G, Singh F, Barini E, Muqit MMK, Brooks SP, Ganley IG*. Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand. Cell Metab 27: 439-449, 2018.

Rodger CE, McWilliams, Ganley IG. Mammalian mitophagy - from in vitro molecules to in vivo models. FEBS J 285: 1185-1202, 2018.

2017

McWilliams TG, Howard L, Wyatt S, Davies AM. TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatalprojection in vivoExp Neurol 298: 97-103, 2017.

McWilliams TG, Muqit MMK. PINK1 and Parkin: emerging themes in mitochondrial homeostasis. Curr Opin in Cell Biol 45: 83-91, 2017.

2016

McWilliams TG, Ganley IG. Life in lights: Tracking mitochondrial delivery to lysosomes in vivoAutophagy 12: 2506-2507, 2016.

Hjerpe R, Bett JS, Keuss MJ, Solovyova A, McWilliams TG,  Johnson C, Sahu I, Varghese J, Wood N, Wightman M, Osborne G, Bates GP, Glickman MH, Trost M, Knebel A, Marchesi F, Kurz T. UBQLN2 mediates autophagy-independent progein aggregate clearance by the proteasome. Cell 166: 935-949, 2016.

McWilliams TG, Prescott AR, Allen GF, Tamjar J, Munson MJ, Thomson C, Muqit MM, Ganley IG. mito-QC illuminates mitophagy and mitochondrial architecture in vivoJournal of Cell Biology 214: 333-345, 2016.

2015

McWilliams TG, Howard L, Wyatt S, Davies AM. Regulation of autocrine signaling in subset of sympathetic neurons has regional effects on tissue innervation. Cell Rep 10: 1443-1449, 2015.

 

Link to Thomas G. McWilliams' ORCiD-profile: https://orcid.org/0000-0002-9570-4152