Precision drugs and gene therapy treatments to activate pro-survival pathways in selected neuronal populations

We investigate molecular mechanisms promoting functional maintenance of dopaminergic neurons, a neuronal population predominantly affected in Parkinson’s disease patients. We are aiming to find novel drugs and therapeutic strategies to support survival of dopaminergic neurons and protect them from cellular stress and pathological protein aggregation.
@ADom_Lab

Dopamine metabolite DOPAL inhibits #Alzheimers-associated amyloid-β fibril formation, but is able to stabilise olig… twitter.com/i/web/status/1…

New review from @LBurbulla & colleagues discusses the convergence of data around alpha-synuclein, mitochondrial, &… twitter.com/i/web/status/1…

The interplay between GCase, α-synuclein & lipids in human models of #Parkinsons by @CGalvagnion & colleagues at… twitter.com/i/web/status/1…

Researchers propose a rapid α‐synuclein seed assay of #Parkinsons cerebrospinal fluid panel which shows a high degr… twitter.com/i/web/status/1…

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