Precision drugs and gene therapy treatments to activate pro-survival pathways in selected neuronal populations

We investigate molecular mechanisms promoting functional maintenance of dopaminergic neurons, a neuronal population predominantly affected in Parkinson’s disease patients. We are aiming to find novel drugs and therapeutic strategies to support survival of dopaminergic neurons and protect them from cellular stress and pathological protein aggregation.
@ADom_Lab

In light of current circumstances, Aiforia invites researchers conducting histopathological investigations of COVID… twitter.com/i/web/status/1…

Further cryo-EM structure data of full-length α-synuclein amyloid fibril with #Parkinsons familial A53T mutation… twitter.com/i/web/status/1…

Gene therapy company @MeiraGTx reports that it anticipates filing an Investigational New Drug application (IND) for… twitter.com/i/web/status/1…

@ckorth @Korthlab_HHU & colleagues report disruption of cellular proteostasis (in human dopamine neurons & mouse br… twitter.com/i/web/status/1…

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