Open positions
Here you can find all the positions that are currently open at HRUH:

- Bioinformatician/postdoctoral researcher (scroll below). Deadline: 28.2.2023.
- M.Sc. thesis project (scroll below). Deadline: 28.2.2023.

Bioinformatician/postdoctoral researcher

The Hematology Research Unit Helsinki (HRUH) & HaikaLab Immuno-oncology group at University of Helsinki, Faculty of Medicine are searching for a skilled bioinformatician/post-doctoral researcher in data science

The Hematology Research Unit Helsinki (HRUH), led by Professor Satu Mustjoki, is a translational research group focusing on tumor immunology, autoimmunity, and personalized medicine in blood cancers. HaikaLab Immuno-oncology group led by Dr. Heidi Haikala is studying immuno-oncology responses and therapy resistance in lung cancer. Both research groups are part of Translational Immunology Research Program (TRIMM) and the iCAN Digital Cancer Precision Medicine Flagship (www.ican.fi). In our ongoing projects we aim to discover more effective immunotherapies, and individual resistance and sensitivity mechanisms using unbiased functional screens at the single cell level (e.g. CRISPR-Cas9 screens, high-throughput drug sensitivity assays) and utilizing primary patient immune and cancer cells in the dynamic co-culture models.

Research group webpages: www.helsinki.fi/hematologywww.haikalab.com

YOUR PROFILE 

  • Highly motivated, curiosity-driven, and experienced applicant with a PhD / MSc in bioinformatics or other related or relevant discipline
  • Fluency with Python, Perl, R or equivalent
  • Experience in biostatistics and applying machine-learning methods 
  • Understanding on and/or demonstrated ability to process genomics data and especially scRNA-seq data is desired
  • Excellent written and verbal communication skills in English, a strong publication record and knowledge in immunology is an advantage
  • Ability to work independently and as a part of a multidisciplinary research team 

WHAT WE OFFER

We offer the opportunity to work in international research environment, with illustrious collaborations and strong link to the clinic. With a state-of-the-art laboratory, we feature a wide range of research techniques and knowledge, from wet lab to bioinformatics, and cherish well-functioning group dynamics. Apart from research work, we provide training and supervision to undergraduate and graduate students. 

The University of Helsinki (UH), founded in 1640, is a vibrant scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world. It is currently investing heavily in life sciences research. UH offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development. 

Read more about the employee benefits at the University of Helsinki and why the University of Helsinki is an excellent career choice: https://www.helsinki.fi/en/about-us/careers

APPLYING FOR THE JOB

The position is available as soon as the selected candidate is available. The project initially allows a two-year fixed-term position. A trial period of 6 months will be applied. Salary will depend upon the applicant's level of skills, knowledge, and abilities and is based on the university salary system and will be around 3400-4000€/month.

Please submit your application via the University of Helsinki Recruitment System by clicking here. Internal applicants (i.e. current employees of the University of Helsinki) should submit their applications through the SAP HR portal.

Please attach the following documents to your application as a single PDF file:

•    Cover letter that details your experience and motivation for applying for the post

•    CV (including publications)

•    Contact details of at least three referees

The deadline for the applications is 28.02.2023.

For further information please contact Satu Mustjoki: satu.mustjoki@helsinki.fi or Heidi Haikala: heidi.haikala@helsinki.fi. If you need support with the recruitment system, please contact recruitment@helsinki.fi.

M.Sc. thesis project

We are looking for a highly motivated master’s thesis student with prior laboratory work experience and passion for science to join our research team at Hematology Research Unit Helsinki (HRUH). For a prospective applicant, we offer an opportunity to work in a project focused on understanding how acquired genetic alterations in blood cells are linked to human health. Our research labs are located in Biomedicum 1 and our group is also affiliated with both the Helsinki Institute of Life Science (HiLIFE) and the Helsinki University Hospital Comprehensive Cancer Center (HUS).

This master’s thesis project is related to the Academy of Finland Clinical Researcher, MD, PhD Mikko Myllymäki’s ongoing study, where our aim is to understand how inherited genetic factors, chronic disease conditions, and medications shape myeloid blood cell function. By leveraging large population-level data sets and disease-specific patient cohorts, we have found clinical associations that we aim to validate using CRISPR-Cas9 methods and myeloid cell lines.

Depending on the student’s interests and project results, it is also possible to continue as a PhD student and to learn data science skills, guaranteeing a wide set of expertise necessary for a successful career in academic translational medicine. Working with us will give you insights into how patient samples, clinical information, and in vitro experiments are translated into cutting-edge science.

To apply, please send your CV and a motivation letter via email to mikko.myllymaki@helsinki.fi.

Deadline: Please send your applications by 28.02.2022

Mikko Myllymäki, MD, PhD
Principal Investigator
Academy of Finland Clinical Researcher
Fellow in Clinical Hematology
Translational Immunology Research Program,
Hematology Research Unit Helsinki, University of Helsinki
and Helsinki University Hospital Comprehensive Cancer Center

Satu Mustjoki, MD, PhD
Professor of Translational Hematology
Director of Translational Immunology Research Program
Hematology Research Unit Helsinki, University of Helsinki
and Helsinki University Hospital Comprehensive Cancer Center