Principal Investigator, Docent in Molecular Genetics
I am a Docent (Adjunct Professor) in Molecular Genetics from the Faculty of Medicine at the University of Helsinki.
I am a molecular biologist by training with specialization in cancer research, mainly in transcription factor function and gene regulation in cancer. My area of expertise is in transcription factor biology using several genome-wide functional genomics methods (ChIP-seq/nexus, bulk/single-cell RNA-seq), chromatin conformation (ATAC-seq, DHS-seq), chromatin architecture methods (in situ HiC, ChIA-PET), cell fate conversion using transcription factors (transdifferention) and high-throughput enhancer assays (MPRAs such as STARR-seq).
I am a Principal Investigator within the Applied Tumor Genomics program of the Research Programs Unit at the Faculty of Medicine, University of Helsinki for the years 2019-2024. As a principal investigator, I am leading the Enhancer Biology lab to understand the role of lineage-specific transcription factors and their collaboration with cancer-specific oncogenes in driving tumorigenesis.
I received my Ph.D. in Pathology and Physiopathology at China Medical University in June, 2019 and then started my postdoc in Biswajyoti Sahu’s lab. Currently, my project focuses on the lineage-specific oncogenic reprogramming and the changes of 3D-genome architecture during the reprogramming process.
I received my Masters' degree in Software Engineering at the Polytechnic of Turin in December, 2016. I started my Ph.D. in Biswajyoti Sahu’s lab in April, 2019.
Now I am working on integrative computational analysis of ChIP-seq, ATAC-seq and RNA-seq data.