Juha Sinisalo Research Group
Coronary artery disease research group is devoted to study all aspects of coronary artery disease. We execute basic and translational research from pathogenesis and immunogenetics to epidemiology and clinical drug trials. Our aim is to discover basic mechanisms behind coronary artery disease, and to influence them so that major adverse events would diminish. Ongoing studies are based on large collected materials such as Corogene-study, ASO-material and the hearts’ explanted during transplantation. Epidemiological studies are based mainly on over ten years follow up data of Corogene-study. Clinical drug trials are located in Meilahti Hospital Heart and Lung Center. Pathogenesis, inflammation, immunogenetics studies are done in collaboration with Haartman-institute.
Background Ischemic heart disease is the most important cause of death worldwide. It is etiologically multifactorial and genetically...
Corogene During June 2006-March 2008 we collected a large sample set of 5295 patients of whom information of coronary angiogram and rich...