Dyslexia is characterized by difficulties in reading and writing. It is a very common learning disorder that severely impacts academic achievement and well-being, posing a substantial economic burden on society.
On December 4, 2020, the dissertation of Anja Thiede, M.Sc. (Tech.), will be examined at the Faculty of Medicine of the University of Helsinki, according to which dyslexia is associated with abnormalities in brain function and structure. Atypical brain function was observed even in newborns at familial risk of dyslexia.
Studies in adults found that certain brain structures as well as brain responses during speech processing were associated with reading skills, as well as the related cognitive functions working memory and phonological processing. Moreover, processing continuous natural speech posed difficulties for the adult dyslexic brain. This is consistent with the assumption that dyslexia stems from atypical language development.
Dyslexic adults also had reduced grey- and white-matter volume in several brain structures important for reading.
Already the brain of newborns processes speech differently
As part of her dissertation, Thiede investigated speech-sound discrimination in newborns by measuring their brain responses to speech sounds and their changes. Half of the infants had an increased risk to develop dyslexia, due to a dyslexic parent, while the other half did not have such risk.
Newborn infants at a heightened risk had atypical speech-discrimination responses. This suggests inherited deficits in brain function during speech processing, which can lead to difficulties in reading acquisition.
Understanding the neural basis of dyslexia helps to develop tools for early identification of infants and children at risk for dyslexia. This would make it possible to target preventive and rehabilitative measures to those who benefit most.
Anja Thiede, M.Sc. (Tech.) defends her doctoral dissertation entitled “Functional and structural correlates of dyslexia and reading-relevant skills in the brain: Evidence from newborns and adults” in the Faculty of Medicine, University of Helsinki, on 4th of December 2020. Professor Jarmo Hämäläinen, University of Jyväskylä, will act as opponent and Professor Teija Kujala, University of Helsinki, as the custos.
The electronic publication of the dissertation can be read at E-thesis service. The defense can be followed only remotely.
The dissertation is part of the research of the Lukivauva project. Read more about studies on dyslexia and its risk on the project website.
Anja Thiede, M.Sc. (Tech.)