In a study conducted at the University of Helsinki, 136 adults adhered to one of three study diets for 12 weeks. One of them corresponded to the average Finnish diet, containing roughly 70% animal-derived protein of total protein, while most of the plant-based protein originated from cereal products. In the second study diet, half of the protein was derived from plant products and the other half from animal products, while the third one contained 30% animal protein and 70% plant-based protein of total protein.
Sources of animal protein, both red and white meat as well as dairy products, were partially replaced with plant-based proteins by adding a diverse range of legumes, nuts, seeds, and cereal products in the diets. Fluid dairy products, which are fortified with vitamin D in Finland, were partially replaced with plant-based drinks not fortified with calcium or vitamin D. The amount of cheese was lower in the diets which contained more plant-based protein compared to the diet rich in animal protein. All diets contained the same amount of fish and eggs.
It was found that both bone formation and resorption increased when part of the animal protein in the diet was replaced with plant protein, which may in the long term be detrimental to bone health. The findings are in line with those recently published from the large EPIC-Oxford population-based study, according to which vegetarians were found to have a greater risk of bone fractures over a follow-up period of 18 years compared to people on a mixed diet.
The researchers suggest the changes in bone metabolism as well as calcium and vitamin D intakes are probably caused by the low amount of dairy products and, consequently, the low amount of calcium and vitamin D consumed. Due to the study design applied, the study subjects were not allowed to use vitamin or mineral supplements during the study period.
“The results could be different if fluid dairy products had been replaced with plant-based drinks fortified with vitamin D and calcium. Then again, the average vitamin D intake was also below the recommended level in the group where subjects consumed the animal protein-rich diet, but not to the same extent as in the other groups” says Docent Suvi Itkonen from the Department of Food and Nutrition, Faculty of Agriculture and Forestry.
Adequate calcium and vitamin D intakes are important for bone health
When adopting an increasingly plant-based diet, it is important, in terms of bone health, to ensure adequate calcium and vitamin D intake. In the case of vitamin D, the recommended intake for adults is 10 micrograms per day. This amount includes total intake from both food and vitamin supplements.
“When consuming plant-based drinks and yoghurt-like products, it is essential to choose the option fortified with calcium and vitamin D. If the daily diet contains no margarines, dairy products or plant-based drinks fortified with vitamin D, and if fish is consumed less than 2–3 times per week, it’s important to ensure adequate vitamin D intake, especially in the dark season, by taking a daily vitamin D supplement.”
The multidisciplinary ScenoProt – Novel protein sources for food security project is funded by the Strategic Research Council of the Academy of Finland. Included in the vision for the project is that in 2030 Finns will consume healthy and sustainably produced food. Previously in the project, it was observed that partial replacement of animal protein with plant protein increased fibre intake as well as improved dietary fat quality and blood lipid profile.
Suvi T. Itkonen, Essi Päivärinta, Tiina Pellinen, Hanna Viitakangas, Juha Risteli, Maijaliisa Erkkola, Christel Lamberg-Allardt, Anne-Maria Pajari. Partial Replacement of Animal Proteins with Plant Proteins for 12 Weeks Accelerates Bone Turnover Among Healthy Adults: A Randomized Clinical Trial. The Journal of Nutrition, Volume 151, Issue 1, January 2021, Pages 11–19, https://doi.org/10.1093/jn/nxaa264