GlucoModicum: Needle-free and painless health monitoring

Based on years of extensive research, GlucoModicum’s scientists have developed a novel, needle-free solution for monitoring glucose and other analytes in interstitial fluid. The first implementation of the solution is a small, pocket-size device.

There are over 400 million diabetics in the world today, and with overweight being a significant risk factor of type 2 diabetes, nearly two billion people are in the risk group.

Monitoring their glucose level is an everyday practice for diabetics. It is mostly done by a needle puncture on the tip of the finger. As this is cumbersome and painful, many people fail to monitor their glucose as often as they should – or they don’t do it at all. Hence, there is a huge need for a convenient needle-free solution.

The novel glucose monitoring solution by GlucoModicum Ltd measures glucose from interstitial fluid without a needle puncture.

In the future, this technology will be miniaturized to fit into smart watches or activity bands. Furthermore, manufacturing costs are low, which makes it suitable for targeting large consumer masses.

Everything started from a coincidence

In 2015, a team of scientists at the University of Helsinki were experimenting with a novel method to transport molecules into tissues without using needles. However, after adjusting certain parameters, they observed just the opposite effect – molecules started to come out.

Later experiments confirmed that the novel method enables rapid extraction of interstitial fluid out of the skin in a painless, convenient, and non-invasive manner. This is the basis of GlucoModicum’s proprietary technology named iFUS.

The researchers have demonstrated that the concentration of glucose in interstitial fluid extracted with iFUS correlates with the concentration of glucose in blood in healthy volunteers.

In addition, interstitial fluid contains information of many other analytes in blood, e.g. certain hormones. Therefore, iFUS can serve as a platform for multiple self-test devices. 

The challenges and opportunities of needle-free glucose monitoring

Multiple technology and pharmaceutical companies are pursuing needle-free glucose monitoring solutions. However, no compelling products are yet in the market. GlucoModicum’s technology breaks a two-decade period of lack of innovations on methods to extract dermal interstitial fluid non-invasively. This opens many exciting opportunities.

"We are carefully monitoring the competitive landscape. At the moment, it seems that iFUS could be the first solid and elegant solution," says the Managing Director of GlucoModicum, Jokke Mäki.

“We believe GlucoModicum is well positioned to create very scalable and profitable business, while bringing a solution to markets which will improve health and quality of life for millions of people."


Strong IPR position

Prototype of iFUS is currently been finalized, and upcoming clinical trials involving patients with diabetes will allow testing of iFUS over a broad glucose range.

GlucoModicum platform technology is patent pending in a growing number of target countries globally. It has already been accepted for grant in Finland by the Finnish Patent and Registration Office.

In addition to the core IPR, GlucoModicum has a broad IPR portfolio covering different dimensions of the overall solution.