SPECT-CT Imaging Unit

SPECT-CT unit hosts a high-performance nanoSPECT/CT imaging instrument enabling quantitative real-time tracking of labelled substances in small animals in 3D at the highest resolution available in the market.

Contact person: J. Arturo García-Horsman, Tel +358-2941-59461 (GSM +358-50-4480761), arturo.garcia@helsinki.fi

Location: Biocentre3, Viikinkaari 1, Viikki Campus, University of Helsinki

Services:

  • In vivo SPECT/CT Imaging
  • Preclinical imaging on disease models
  • Ex vivo distribution validation
  • Tracer preparation (in collaboration with HiLIFE infrastructure Radiopharmaceutical chemistry)

Instruments:

  • nanoSPECT/CT camera system with four detectors, and multi-pinhole collimators for the most efficient detection. This makes the system with the highest resolution in the market.
  • Workstation with state-of-the-art Tera-Tomo™ 3D SPECT reconstruction software which includes CT correction
  • Class B radiation laboratory for in-house radiotracer preparation

Applications:

SPECT/CT is suitable for applications in drug research, neuroscience, oncology, and others as:

  • Bio-distribution studies of a single molecule, the delivery system, or the vehicle (separate or in parallel)
  • Drug delivery
  • Drug pharmacodynamics/pharmacokinetics
  • Target validation
  • Neurotransmitter-specific neuronal integrity
  • Tumour integrity

User fees:

The research infrastructure is supported by University of Helsinki (HiLIFE, Faculty of Pharmacy) and Biocenter Finland. The academic prices (excl. VAT) are listed below. Please, ask a quotation for your project. Industrial customers, please contact García-Horsman for prices.

Service

€/h

€/day

SPECT/CT scan

110

110

Operator

45

 

Veterinary nurse

45

 

Use of image analysis software

10

 

Image analysis

45

 

 The hosting research group:

http://www.cdr.fi/spect-ct-imaging-core-facility