Nuclear actin lab

The cell nucleus is a highly organized and dynamic organelle. This dynamic organization is required for essential nuclear processes, such as gene expression and maintenance of genomic integrity. We study how actin operates in the nucleus to regulate nuclear organization and consequently nuclear processes. In the cytoplasm, actin has a well-established role as a component of the cytoskeleton, and plays important roles for example in cell motility and morphology. In the nucleus, actin has been linked to many processes that regulate gene expression, such as transcription factor regulation, RNA polymerase function and chromatin remodeling, as well as to DNA damage response. However, the molecular mechanisms by which actin functions during these key nuclear events are largely unclear.

Vartiainen lab on Twitter

@VartiainenLab

Very interesting paper from the Belmont-lab! Congratulations to Joseph, the very first PhD from our lab @BIOTECH_UHtwitter.com/i/web/status/1…

Congratulations to @BIOTECH_UH @HiLIFE_helsinki scientists Ville Hietakangas, @PekkaKatajisto, Pekka Lappalainen, S… twitter.com/i/web/status/1…

Our new review on nuclear actin in Current Opinion in Cell Biology is freely available at sciencedirect.com/science/articl…twitter.com/i/web/status/1…

Thank you @grosse_lab and other organizers for the Actin Assembly for Intracellular Functions meeting last week! Su… twitter.com/i/web/status/1…