Pia first discovered ”microparticles” during her PhD studies, while studying the role of collagen receptors in platelet functions including procoagulant activity. Platelet-derived EV staining of fibrin strands in thrombus-formation mimicking system of blood flow generated her first EV publication in
In 2016, the EV group jointly with
Since 6 February 2024, Pia is the President of the Finnish Society of Extracellular Vesicles (
Johanna is interested in the EV-mediated communication between platelets and other immune cells and studies the biophysical and therapeutic properties of platelet-derived EV (PEV) subpopulations. Johanna’s research focuses on tailoring PEV generation with different platelet activations and establishing new methods for physicochemical and functional characterization of PEVs at the subpopulation level. Johanna has previously set up a novel asymmetric flow field-flow fractionation method for subpopulation analyses in the EV Group and EV Core (
Zeynep received her
Zeynep has been working in the PLEASER project since 2022. She is using RNA sequencing and different cell-based functional assays to investigate the interaction between cancer cells and platelets aided through EVs in a 3D melanoma model. Zeynep’s other project in the EV group was to apply metabolomics to discover the candidate biomarker molecules in cancer EVs within the
Snehadri has been interested in the field of EVs since his Master's studies. He did his
In his PhD work, Snehadri has been exploring the role of EVs in the microenvironment of bone tumour (osteosarcoma) in 2D and 3D settings. He divides his time between the EV group and the Oral cancer research group (PI: Tuula Salo) in the Meilahti campus.
Zhilin received her master's degree in oncology from Harbin Medical University, China, focusing on the promotion role of circRNAs in thyroid cancer.
Christina joined the EV group as a technical assistant to work with platelet derived EVs and their characterization before starting her doctoral studies. She is interested in the EV protein corona, a “molecular cloak” that influences EV functions and cellular interactions, and her PhD will focus on the protein corona on platelet derived EV and its implications for diagnostics and therapeutics.
Christina’s
Rosabella has been working for EV-Core since 2019 and branched out into EV-group in the summer 2021, helping with several projects as a technical assistant.
Outside of her work in the EV-group, Rosabella studies physiology at the University of Helsinki and is working on her bachelors thesis on 'Extracellular vesicles as biomarkers in neurodegenerative diseases'. After that she will focus on her masters degree in neurophysiology while continuing to work with EVs at the EV-Core.
Helin has worked in the University of Helsinki since 2011 as a technical assistant, and joined the EV group in 2022.
She has a Master's degree in applied chemistry and biotechnology from Tallinn University of Technology.
As an associate group member of the EV group, Maija explores the commercialization options for an innovative and scalable EV isolation method,
Maija also studies the EV contained (mi)RNA biomarkers for diabetic kidney disease and urological cancers at
Mari is currently a visiting researcher in the EV group and a supervisor of Johanna and Zeynep. Mari’s research focuses on the potential of platelet-derived EVs as natural therapeutics in regenerative medicine, and how activating platelets with various agonists affects the molecular cargo of platelet-derived EVs. Mari has a long track record in omics (proteomics and metabolomics) relevant in many projects. For example, she is studying the potential metabolomic fingerprint of cancer EVs with Zeynep. From September 2021-2023, Mari worked in the PLEASER project studying the effect of cancer-EVs on platelets as a university researcher.