Pia first bumped into ”microparticles” during her PhD studies, when she saw a platelet-derived staining of fibrin strands in thrombus-formation mimicking system of blood flow resulting in her first EV publication in 1996 . For the PhD, she studied the role of collagen receptors in platelet functions including procoagulant activity. In 2000-2004, she did a post doc in the University of Cambridge U.K, on platelet collagen receptors. Upon returning to Finland, she worked as an Academy of Finland –funded independent post doctoral researcher and research fellow with the aim to develop tools for integrin affinity states with phage display before becoming a university lecturer in Biochemistry of Health in 2008. By then, the field of EVs had started to bloom, enabling her to return to the topic of her passion. She has also been lucky to spark others to join in the quest to try to understand the powerful communication of the cells’ own social media, EVs, thereby generating the EV group.

In 2016, the EV group was proud to open the world’s first a core facility dedicated to EVs jointly with Dr. Maija Puhka in FIMM to offer our expertise to other researchers in Finland and internationally.
 

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Katariina is interested in the diagnostic and therapeutic potential of EVs. Currently, she studies platelet-derived EVs in the context of cardiovascular diseases. She is especially interested in how different platelet activators relevant to cardiovascular diseases affect the number and composition of platelet-derived EVs, and how such EVs may contribute to the disease development. Katariina is also part of a EURAMET EMPIR project aiming to standardize concentration measurements of EVs for medical diagnoses.

In her Academy of Finland funded project Mari focuses on platelet-derived EVs and their potential use in regenerative medicine as natural therapeutics. She is interested in omics (proteomics and metabolomics) and currently investigates how the activating platelets with various agonists affects the cargo of platelet-derived EVs. She also coordinates the EV core in Viikki.

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Maija works as a project manager to explore commercialization options for an innovative and scalable EV isolation method (Business Finland TUTL program and Spark Finland mentoring). She is especially interested to help researchers to grab the potential of the fast developing field with improved EV technologies. The EV Core facility, of which functions Maija is heading at FIMM, has the same focus. Maija also studies the EV contained (mi)RNA biomarkers for diabetic kidney disease and urological cancers at FIMM with MD, PhD, prof. Leif Groop and Antti Rannikko.

Maria's PhD-project focuses on the vesicle-mediated interaction mechanisms in cell communication. She is interested in how cell activation effects on cell vesiculation and vesicle properties, especially in hypoxic conditions. The PhD project is also supervised by Dr. Mikaela Grönholm from Department of Biosciences.

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Sami is a PhD student working with platelet-derived EVs. The thesis project aims to shead light on the molecular mechanisms of intercellular messaging of EVs. The thesis project is also supervised by Dr. Saara Laitinen from Finnish Red Cross Blood Service.

TUHAT

KeKe is our technical assistant for the FastEV project and works closely with Maija to develop innovative EV isolation method and explore commercialization possibilities. He is especially interested in using the state-of-the-art technologies and innovations for EV isolation.

 

Maarit Neuvonen, PhD, currently working at Targovax Oy

Snehadri SInha, MSc, PhD student at medical Faculty, UH

Maarit Takatalo-Laine, PhD, currently working at Orion Diagnostica

Elisa Lazaro Ibañez, PhD, currently working at Astra Zeneca

Saara Kauremaa, BScs

Jesus Gullon Sanz, BSc

Anna Lindelöf BSc

Manuel de Aledo Gonzales BSc