Bioinformatics is an interdisciplinary research field combining computer science methods and statistical/mathematical modelling to analyse biological measurement data. With the recent advances in high-throughput sequencing, bioinformatics software tools are now enabling completely new ways of conducting research in genetics, genomics, and transcriptomics, with direct applications in cancer research and other biomedical areas that make use of sequencing. Often the real breakthroughs arise in the collaboration between method developers and domain experts. The Bioinformatics research groups aim for building a solid basis for method development and introducing novel applications of bioinformatics to advance the Life Science (strategic focus area of) research at the University of Helsinki.