Our collaborative work with Aalto University, group of prof. Mauri Kostiainen, has been focused on the testing lignin nanoparticles for cancer applications.
"Working with physical chemist Hélder A. Santos of the University of Helsinki, Kostiainen carboxylates lignin, which he then makes into nanoparticles using the same method as Österberg. The carboxylate groups allow the researchers to functionalize the lignin nanoparticles with cell-penetrating proteins and pH-responsive polymers to help deliver anticancer drugs into tumor cells. Loaded with benzazulene, a poorly soluble drug, the nanoparticles are effective at killing cancer cells in cultures and remain intact under conditions meant to simulate the body (Nanomedicine 2017, DOI: 10.2217/nnm-2017-0219)."
Volume 96 Issue 7pp. 19-22
Issue Date: February 12, 2018 | Web Date: February 6, 2018
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