March 13, 2025
Venue: Biomedicum Helsinki 1, Haartmaninkatu 8, Helsinki, Finland. Talks will be held in Lecture hall 1 (C wing in the P floor), with sponsor exhibitions outside the lecture hall.
Registration will open on Jan 23 at https://elomake.helsinki.fi/lomakkeet/133078/lomakkeet.html
The symposium will be a one day event and is combined with a hands-on wet-lab and data-analysis courses for students. The symposium covers broad areas of single cell omics from spatial interactions to gene regulatory networks, with methodologies ranging from multiomics to RNA velocity and long-read sequencing, applied in a wide range of biological contexts: brain development and aging, skin physiology, cardiovascular diseases, and cancer.
9:00 OPENING WORDS
SESSION 1: GENE REGULATORY NETWORKS. Chair: Helena Kilpinen
9:05 Judith Zaugg (University of Basel): Gene regulatory networks integrate genetic and epigenetic disease mechanisms in hematology
9:40 MariIke Kuijjer (Univ. of Helsinki, Univ. of Oslo): Single-cell network modeling with SCORPION identifies regulatory drivers of colorectal cancer progression
10:05 10x Genomics: 10x Genomics: See biology in new ways (Johanna Stergiadou)
10:10- 10:40 Coffee & poster set-up
SESSION 2: SINGLE CELL OMICS OF PATHOLOGIES. Chair: Merja Heinäniemi
10:40 Heidi Haikala (Univ. of Helsinki, Tampere Univ.): Studying lung cancer treatment resistance using single cell methods
11:05 Minna Kaikkonen-Määttä (Univ. of Eastern Finland): Mapping the genetic basis of atherosclerosis using single cell genomics
11:30 BD Biosciences: BD Rhapsody: True Single Cell Multiomics Platform, Powered by
Microwell technology for Unparalleled Flexibility and Performance. (Jouni Rantanen)
11:35 PARSE Biosciences, Smashing the Limits of Single Cell Transcriptomics - Introducing Evercode (Anne Helness)
11:40-13:00 Salad buffet lunch
SESSION 3: FROM CELLS TO TISSUES. Chair: Saara Ollila
13:00 Maria Kasper (Karolinska Institute): The Plasticity of Skin Cells: Key to Maintaining Tissue Function
13:25 Elisa Manieri (Univ.of Veterinary Medicine Vienna): From scRNAseq to cell function in crosstalk
14:00 Illumina: lllumina Single Cell 3' RNA Prep: Flexible, Scalable, and affordable single cell analysis in any lab (Vivek Mishra)
14:05- 15:05 Posters & coffee
SESSION 4: SPACE AND TIME. Chair: Anna Vähärautio
15:05 Nanopore, What you're missing matters: New dimensions of biology revealed by Nanopore full-length sequencing of single-cell and spatial assay (Penelope Shah)
15:10 Gioele La Manno (EPFL): Spatiotemporal methods to chart the cell states of brain development
15:45 HiLIFE seminar: Hagen Tilgner (Weill Cornell): Brain isoform expression at single-cell resolution in (developmental) time and (anatomical) space – and in neurodegeneration
16:30 – 17:30 Poster session with sparkling & snacks
Anna Vähärautio, Jenni Lahtela, Saara Ollila, Helena Kilpinen, Merja Heinäniemi, Iivari Kleino, Rafa Najumudeen, Laura Elo, Eija Korpelainen.
Symposium is sponsored by: DPBM, Illumina, 10xGenomics, Nanopore, BD Biosciences, Scellex, SCALE Biosciences, Triolab Oy, PARSE Biosciences, Element Biosciences