Research

An international Scientific Advisory Board selects the research programmes in Faculty of Medicine through a competitive application procedure every six years.
 

TRANSMED students do their Master's theses in research groups. The group can be chosen from any of the research groups on the campus. Many students have also contributed to scientific publications during their TRANSMED studies. Some examples:

S Gramolelli, J Cheng, I Martinez-Corral, M Vähä-Koskela, E Elbasani, E Kaivanto, V Rantanen, K Tuohinto, S Hautaniemi, M Bower, C Haglund, K Alitalo, T Mäkinen, TV Petrova, K Lehti and PM. Ojala. PROX1 is a transcriptional regulator of MMP14. Sci Rep. 2018; 8:9531

Hulmi JJ, Nissinen TA, Räsänen M, Degerman J, Lautaoja JH, Hemanthakumar KA, Backman JT, Ritvos O, Silvennoinen M, Kivelä R. Prevention of chemotherapy-induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscle. J Cachexia Sarcopenia Muscle 2018; 9:417-432.

Tang J, Tanoli ZU, Ravikumar B, Alam Z, Rebane A, Vähä-Koskela M, Peddinti G, van Adrichem AJ, Wakkinen J, Jaiswal A, Karjalainen E, Gautam P, He L, Parri E, Khan S, Gupta A, Ali M, Yetukuri L, Gustavsson AL, Seashore-Ludlow B, Hersey A, Leach AR, Overington JP, Repasky G, Wennerberg K, Aittokallio T. Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions. Cell Chem Biol. 2018; 25:224-229.

Sulkava S, Ollila HM, Alasaari J, Puttonen S, Härmä M, Viitasalo K, Lahtinen A, Lindström J, Toivola A, Sulkava R, Kivimäki M, Vahtera J, Partonen T, Silander K, Porkka-Heiskanen T, Paunio T. Common Genetic Variation Near Melatonin Receptor 1A Gene Linked to Job-Related Exhaustion in Shift Workers. Sleep. 2017; 40(1).

Korpi ER, Linden AM, Hytönen HR, Paasikoski N, Vashchinkina E, Dudek M, Herr DR, Hyytiä P. Continuous delivery of naltrexone and nalmefene leads to tolerance in reducing alcohol drinking and to supersensitivity of brain opioid receptors. Addict Biol. 2017; 22:1022-1035.

Al-Samadi A, Awad SA, Tuomainen K, Zhao Y, Salem A, Parikka M, Salo T. Crosstalk between tongue carcinoma cells, extracellular vesicles, and immune cells in in vitro and in vivo models. Oncotarget. 2017; 8:60123-60134.

Sulkava S, Ollila HM, Alasaari J, Puttonen S, Härmä M, Viitasalo K, Lahtinen A, Lindström J, Toivola A, Sulkava R, Kivimäki M, Vahtera J, Partonen T, Silander K, Porkka-Heiskanen T, Paunio T. Common Genetic Variation Near Melatonin Receptor 1A Gene Linked to Job-Related Exhaustion in Shift Workers.  Sleep. 2017; 40(1).

S Fang, H Nurmi, K Heinolainen, S Chen, E Salminen, P Saharinen, H K A Mikkola, K Alitalo. Critical requirement of VEGF-C in transition to fetal erythropoiesis. Blood. 2016; 128:710-720.

Fu Y, Gaelings L, Söderholm S, Belanov S, Nandania J, Nyman TA, Matikainen S, Anders S, Velagapudi V, Kainov DE. JNJ872 inhibits influenza A virus replication without altering cellular antiviral responses. Antiviral Res. 2016;133:23-31.

Neuroscience Center (NC) focuses on research in molecular and cellular neuroscience, developmental neuroscience, cognitive and systems neuroscience, and basic research of the nervous system diseases. It currently has 20 research groups and operates mainly in the Meilahti medical campus with some activities also at the Viikki campus.

NC hosts state-of-art for imaging facility including three multiphoton microscopes for fast scanning 3D brain imaging and optogenetic stimulation in fish and awake rodents, as well as behavioural facilities for mouse and zebrafish and a neuronal cell culture unit.

NC is a unit of Helsinki Institute of Life Science (HiLIFE), a scientifically and collaborates locally with faculties and organisations with an interest in neuroscience.

More information about the Neuroscience Center.

Institute for Molecular Medicine Finland (FIMM) is an international research institute in Helsinki focusing on human genomics and personalized medicine. FIMM integrates molecular medicine research, Technology Centre and Biobanking Infrastructures “under one roof” and thereby promotes translational research and adoption of personalized medicine in health care.

FIMM is part of Helsinki Institute of Life Science (HiLIFE) and hosted by the University of Helsinki. 

More information on the website of the Institute for Molecular Medicine Finland (FIMM).