Our research aims at understanding the diversity and significance of the tissue-resident human virome. Through advanced sequencing techniques, innovative diagnostics and bioinformatics-driven approaches, we are uncovering new perspectives on host-pathogen interactions and the impact of persistent viruses on human health and disease.
The human virome

Our research on the human virome encompasses a broad range of studies on the eukaryotic DNA viruses inhabiting the human body, to determine their role in health and disease. Using custom-designed next generation sequencing and bioinformatics tools, we explore the genomic composition, diversity and clinical impacts of the viral pathogens persisting in human tissues lifelong. We have also designed and developed highly sensitive and specific nucleic acid testing methods (quantitative PCR) for cutting-edge detection of viral DNAs from various sample sources.

Diagnostics innovation

We have profound and longstanding expertise in transformative approaches for antiviral immunity and infection timing analyses. Via in-depth analysis of immunoglobulin interactions, our antibody avidity diagnostics have already saved globally over 100 000 human lives. We innovate on rapid point-of-care diagnostics and non-invasive unconventional sampling. Our forthcoming immunodiagnostics aim at revolutionizing the medical management of infectious and autoimmune diseases, as well as vaccinations.

Clinical significance of DNA viruses

We investigate viral pathogenesis and host-pathogen interactions through a multidisciplinary approach, integrating basic science research with clinical medicine. Collaborating closely with expert clinicians, we examine the role of viruses in diverse conditions, including autoimmune diseases, chronic inflammatory disorders, and immunodeficiencies.

Our investigations entail comprehensive genomic analysis, complemented by nucleic acid-based, serological and in situ assays, to unravel complex clinical traits. 


We create innovative bioinformatic tools for the identification, assembly, and analysis of viral genomes. Our focus is on developing highly sensitive, automated, and artificial intelligence-driven pipelines for the reconstruction of viral genomic data. We have made publicly available our custom pipeline, TRACESPipe, which features cross-examination of sequencing data from different sources.