ViPS Invited Seminar November 2022

Chad Niederhuth, Michigan State University, USA

Date: 16th November 2022

Time: 13:00

Title: Intertwined Evolution of Plant Genomes and Epigenomes

Location: Lecture room B5, Forest Sciences Building, Latokartanonkaari 7-9 and remotely via Zoom

Host: Tanja Pyhäjärvi

Abstract: Eukaryotic genomes are organized and regulated by the epigenome. The epigenome includes a range of chromatin marks such as DNA methylation, histones, and histone modifications, which differentiate regions of euchromatin and heterochromatin. While the epigenome is frequently treated as an independent layer of genomic regulation, the epigenome is in fact intimately tied to and has evolved within the context of the underlying DNA sequence. The epigenome in turn directly and indirectly shapes the evolution of the genome. In this seminar I will discuss the correlated evolution of plant genomes and epigenomes, in particular recent work in my lab on the role of chromatin and transcriptional regulation in duplicate gene evolution and the impact of structural variation in local adaptation. 

I am broadly interested in the evolution and functions of plant genomes and epigenomes. My lab works with a diverse range of plant species and even non-plant species such as dogs. Examples of ongoing work includes the evolution of cold-stress transcriptional responses in maize and sorghum, cis-regulatory elements in switchgrass drought responses, the role of transcriptional regulation and structural variation in local adaptation, and the impact of clonal propagation on epigenomic and genomics stability. 

Read more about Chad's work

Related publications:

Bewick, A. J., C. E. Niederhuth, L. Ji, N. A. Rohr, P. T. Griffin, J. Leebens-Mack, and R. J. Schmitz. 2017. 'The evolution of CHROMOMETHYLASES and gene body DNA methylation in plants', Genome Biol, 18: 65.

Bird, K. A., C. E. Niederhuth, S. Ou, M. Gehan, J. C. Pires, Z. Xiong, R. VanBuren, and P. P. Edger. 2021. 'Replaying the evolutionary tape to investigate subgenome dominance in allopolyploid Brassica napus', New Phytol, 230: 354-71.

Kenchanmane Raju, Sunil K., S. Marshall Ledford, and Chad E. Niederhuth. 2021. 'DNA methylation signatures of duplicate gene evolution in angiosperms', bioRxiv: 2020.08.31.275362.

Niederhuth, C. E., A. J. Bewick, L. Ji, M. S. Alabady, K. D. Kim, Q. Li, N. A. Rohr, A. Rambani, J. M. Burke, J. A. Udall, C. Egesi, J. Schmutz, J. Grimwood, S. A. Jackson, N. M. Springer, and R. J. Schmitz. 2016. 'Widespread natural variation of DNA methylation within angiosperms', Genome Biol, 17: 194.

Ritter, E. J., and C. E. Niederhuth. 2021. 'Intertwined evolution of plant epigenomes and genomes', Curr Opin Plant Biol, 61: 101990.