ViPS Invited Seminar December 2018

Francois Parcy, Biosciences and Biotechnology Institute of Grenoble, France

Date: 12th December 2018

Time: 13:15

Title: A structural journey with floral regulators

Location: Seminar room 2012, Biocentre 2, Viikinkaari 5

Host: Paula Elomaa

Abstract: In Arabidopsis like in many other plants, flowers are initiated on the flanks of the shoot apical meristem. The position of flowers is determined by the phytohormone auxin and the Auxin Response Factor Monopteros/ARF5 protein. Soon afterwards, the LEAFY transcription factor contributes to the emergence and the floral fate of the newly formed flower meristem. We used a combination of molecular genetics, structural biology, genomics and modelling to better understand how these transcription factors to access to specific genomic regions and control gene expression.

Francois Parcy studies how flower development is controlled at the transcriptional and chromatin levels. His lab focuses in particular on the LEAFY and ULTRAPETALA1 proteins and uses the development of flowers as a model process to address general questions such as the interplay between transcription factors (TF) and chromatin remodeling proteins, the modeling of sequence specific DNA recognition by TF or the evolution of regulatory networks.

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Related publications:

Chahtane H, Zhang B, Norberg M, LeMasson M, Thévenon E, Bako L, Benlloch R, Holmlund M, Parcy F, Nilsson O and Vachon G. LEAFY activity is post-transcriptionally regulated by BLADE ON PETIOLE2 and CULLIN3 in Arabidopsis.
New Phytologist, 2018, 220(2): 579-592

Engelhorn J, Wellmer F and Carles CC. Profiling histone modifications in synchronized floral tissues for quantitative resolution of chromatin and transcriptome dynamics. Methods in Molecular Biology, 2018, 1675: 271-296

Vachon G, Engelhorn J and Carles CC. Interactions between transcription factors and chromatin regulators in the control of flower development. Journal of Experimental Botany, 2018, 69(10): 2461-2471