Publications

Selected publications from the lab

1.    Conway JRW#, Isomursu A, Follain G, Härmä V, Jou-Ollé E, Pasquier N, Välimäki EPO, Rantala JK and Ivaska J# (2023) Defined extracellular matrix compositions support stiffness-insensitive cell spreading and adhesion signaling. PNAS 120(43):e2304288120.  
#Co-corresponding authors

2. Conway JRW#, Dinç DD, Follain G, Paavolainen O, Kaivola J, Boström P, Hartiala P, Peuhu E and Ivaska J# (2023) IGFBP2 secretion by mammary adipocytes limits breast cancer invasionScience Advances 9(28): eadg1840.       
#Co-corresponding authors

3. Conway JRW, Warren SC, Lee Y-K, McCulloch AT, Magenau A, Lee V, Metcalf XL, Stoehr J, Haigh K, Abdulkhalek L, Guaman CS, Reed DA, Murphy KJ, Pereira BA, Mélénec P, Chambers C, Latham SL, Lenthall H, Deenick EK, Ma Y, Phan T, Lim E, Joshua AM, Walters S, Grey ST, Shi Y-C, Zhang L, Herzog H, Croucher DR, Philp A, Scheele CLGJ, Herrmann D, Sansom OJ, Morton JP, Papa A, Haigh JJ, Nobis M and Timpson P (2023) Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse. Science Advances 9(17): eadf9063.

4. Conway JRW and Jacquemet G (2019) Cell matrix adhesion in cell migration. Essays in Biochemistry63(5): 535-551.

5. Conway JRW, Herrmann D, Evans TJ, Morton JP and Timpson P (2019) Combating pancreatic cancer with PI3K pathway inhibitors in the era of personalised medicineGut. 68(4): 742-758.

6. Conway JRW, Warren SC, Herrmann D, Murphy KJ, Cazet AS, Vennin C, Shearer RF, Killen MJ, Magenau A, Mélénec P, Pinese M, Nobis M, Zaratzian A, Boulghourjian A, Da Silva AM, del Monte-Nieto G, Adam ASA, Harvey RP, Haigh JJ, Wang Y, Croucher DR, Sansom OJ, Pajic M, Caldon CE, Morton JP and Timpson P (2018) Intravital imaging to monitor therapeutic response in moving hypoxic regions resistant to PI3K pathway targeting in pancreatic cancer. Cell reports. 23(11): 3312-3326.

7. Conway JRW, Vennin C, Cazet AS, Herrmann D, Murphy KJ, Warren SC, Wullkopf L, Boulgourjian A, Zaratzian A, Da Silva AM, Pajic M, Morton JP, Cox TR and Timpson P (2017) Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology. Scientific Reports. 7(1): 16887.

8. Conway JRW, Warren SC and Timpson P (2017) Context-dependent intravital imaging of therapeutic response using intramolecular FRET biosensors. Methods. 128:7 8-94.

9. Conway JRW, Carragher NO and Timpson P (2014) Developments in preclinical cancer imaging: innovating the discovery of therapeutics. Nature reviews. Cancer. 14(5): 314-328.