Group members of the Tumor Progression and Metastasis Lab

Prof., Principal Investigator (Tumor Progression & Metastasis, Helsinki, Finland)

Director of the Laboratory Animal Centre (Helsinki, Finland)

After completing her Ph.D. in 1996 at the University of Helsinki, studying the membrane association and intracellular localization of virus methyltransferase, Prof. Pirjo Laakkonen joined Prof. Erkki Ruoslahti’s lab at the Burnham Institute of California as a postdoctoral fellow. During four years, she focused her research on developing and perfecting the phage display technology and successfully discovered novel targeting peptides specific to the tumour tissue and tumour lymphatics network. Back to Finland she founded her own research group of Translational Cancer Biology in the Research Program Unit of the Faculty of Medicine, University of Helsinki, Finland. She currently leads key research projects on the identification of new molecular targets involved in the tumorigenesis and invasive spread of peripheral and central nervous system primary and secondary metastatic lesions.

Translational Cancer Medicine Research Program
Biomedicum Helsinki
P.O. Box 63, Haartmaninkatu 8
00014 University Helsinki

Tel. Office  +358 2 941 58100 /cell phone +358 50 448 9100
pirjo.laakkonen@helsinki.fi

Pirjo Laakkonen in research portal

Ph.D., Post-doctoral researcher

Since 2015, Dr. Vadim Le Joncour has joined Prof. Laakkonen’s group and works on the preclinical validation of molecular nano-cargos displaying targeting peptides previously identified via the phage display technique. More specifically, his work focuses on different methods used to increase the permeability towards the blood-brain-barrier and the specific targeting of invasive glioblastoma cells. He is also interested in the fine molecular mechanisms involved in the metastatic spread of peripheral neoplasms that could constitute key targets for new drugs development.

Translational Cancer Medicine Research Program
Biomedicum Helsinki, office A525b
P.O. Box 63, Haartmaninkatu 8
00014 University of Helsinki

cell phone +358 417229335
vadim.lejoncour@helsinki.fi
@theneonDIM_on

Vadim Le Joncour in research prortal
Vadim Le Joncour in Orcid
Vadim Le Joncour in LindedIn

Ph.D., Post doctoral researcher

BSc in molecular biology (University of Leon; Spain) and PhD in molecular pathogenesis of infectious diseases (Bristol University; UK). Dr. Monzo continued his research career in molecular neurosciences focusing on neural progenitor cell migration and glioma cell spread (Auckland University; New Zealand), and is currently researching the development of molecular target therapies for malignant glioma (University of Helsinki; Finland).

Hector Monzo in research portal

M.sc., Ph.D. student

Ms. Filppu received herMaster’s degree in the field of cell and molecular biology from the University of Jyväskylä. She is currently a graduate student in Doctoral Programme in Biomedicine (DPBM) at the University of Helsinki. Her research interests are focused on molecular biology of cancer and translational research. With a particular interested in malignant gliomas, glioma stem cells, and tumor immunology. Pauliina's research project aims to provide novel insight into the complex yet poorly understood molecular mechanisms of how glioma stem cells contribute to malignant tumor growth and their interaction with the immune system which could be translated into benefit of patients.

Translational Cancer Medicine Research Program
Biomedicum Helsinki
P.O. Box 63, Haartmaninkatu 8
00014 University Helsinki

pauliina.filppu@helsinki.fi

Pauliina Filppu in research portal

M.sc., Ph.D. student

Mr. Ayo is an early stage researcher in the field of brain tumor and metastasis at the University of Helsinki, Finland. He started his doctoral research in September, 2015 under the Marie-Sklodawska-Curie ETN MAGICBULLET European Training Network. Previously, after completing a M.Sc. in Cancer Research from the National University of Ireland Galway, Republic of Ireland from September 2013 to November 2014. His previous research work was focusing on the crosstalk between endoplasmic reticulum stress and autophagy. Prior to this, Mr. Ayo obtained a B.Sc. in Biochemistry from the University of Ado Ekiti, Nigeria.

Translational Cancer Medicine Research Program
Biomedicum Helsinki
P.O. Box 63, Haartmaninkatu 8
00014 University Helsinki

Tel. +358-4007-58076
abiodun.ayo@helsinki.fi

Abiodun Ayo in research portal

M.sc., Ph.D. student

With a Bachelor’s degree in Genetic Engineering from SRM University, India and a Master’s degree in RNA Biology from Université de Lorraine, France; Mr. Jayendrakishore joined the laboratory of Prof. Pirjo Laakkonen as a graduate student under the ETN MagicBullet programme.

With Glioblastoma as an area of interest, his current work focuses on identifying/validating new therapeutic targets and drug conjugates to investigate their activity in vitro and in vivo. Jayendrakishore's project involves emerging techniques like CRISPR/Cas 9 system as well as traditional molecular cell biology

Translational Cancer Medicine Research Program
Biomedicum Helsinki
P.O. Box 63, Haartmaninkatu 8
00014 University Helsinki

jk.tanjoreramanathan@helsinki.fi

Jayendrakishore Tanjore Ramanathan in research portal