Mohieddin Jafari earned a Ph.D. in Applied Proteomics in 2013 from the Beheshti University of Medical Sciences under the supervision of Professor Mehdi Sadeghi. During his predoctoral studies (2011) at the Proteomics Resource at the Harvard School of Public Health (HSPH), he concentrated on protein fractionation in mass spectrometry-based proteome profiling under the supervision of Professor Alexander Ivanov. In 2015, he graduated from the Systems Biology Specialization Certificate program at the Icahn School of Medicine at Mount Sinai, where he focused on network biology applications employing high-throughput data mining and network analysis tools. In 2018, I began working as a senior researcher at the University of Helsinki, following 1+3 years as a postdoc and PI at the Pasteur Institute of Iran. He began his career at FIMM for one year before joining the ONCOSYS Research Program Unit, Dept. of Pharmacology, and Clinical Proteomics Core Facility, for more than three years. In 2020, he obtained his Docentship in Bioinformatics from Helsinki University. In 2023, Dr. Jafari launched his independent career as a principal investigator in the Systems Pharmacology Research Group, Department of Biochemistry and Developmental Biology, where he received a four-year appointment as an ERKKO Personal Grant (2023-2027) and an Academy of Finland Research Project fund (2020–2024).
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Mehdi Mirzaie received his Ph.D. in Applied Mathematics with a focus on Bioinformatics from Iran's Shahid Beheshti University. He presented a novel method for protein fold recognition based on game theory in his thesis. From 2010 to 2014, I worked as an assistant professor at Shahid Beheshti University of Medical Sciences, where I primarily taught courses in statistical bioinformatics, network science, and computational systems biology. From 2015 to 2020, I worked as an assistant professor in the department of Biomathematics, where I supervised master's students and taught game theory, stochastic processes, and bioinformatics. In 2021, he relocated to Finland to work as a postdoctoral researcher in drug combination prediction.
Elham is a doctoral researcher whose main focus is on exploring protein–drug, protein–metabolite, and protein-protein interactions. She received her BSc degree in cellular and molecular biology, completed her M.Sc. in clinical biochemistry at Semnan University of Medical Sciences in 2020, and joined Dr. Jafari’s research group in 2021 to pursue her PhD. During her master's, she focused on drug target interaction and mechanism of action identification using a high-throughput proteomic technique. Currently, she is developing this proteomic technique into combination therapy for acute myeloid leukemia.
Research interests: cancer research, molecular systems biology, proteomics, mass spectrometry, bioinformatics, and drug combination analysis.
Rashwita is a master's student of Microbiology and Microbial Biotechnology at the University of Helsinki. She received her bachelor's degree from the University of Surrey in Microbiology. Her research background is in virology, focusing on studying antiviral host response in insect cells and investigating virus-host protein interactions in mammalian cells. Rashwita has joined our lab as a summer intern to delve deeper into the principles of systems pharmacology. Her interest in drug discovery has led her to seek further knowledge and experience in this field.
Research interests: drug discovery, systems pharmacology, proteomics, virus-host protein interactions.