Translational Stem Cell Biology and Metabolism (STEMM) program brings together eleven research groups and four associated clinical researchers interested in cellular metabolism as a driving force in tissue homeostasis, cellular differentiation and degenerative diseases. Many of the groups take advantage of the possibilities of stem cell and genome editing technologies to understand molecular disease mechanisms in order to develop innovative treatments. Close ties to pediatric and neurology clinics enable efficient use of our research findings for diagnosis, patient care and counseling.