At the Rodent and Disease Ecology lab, we explore this question from a multidisciplinary approach, combining population, landscape, behaviour and movement ecology with virology, molecular biology, epidemiology, ecotoxicology and social sciences to understand spatio-temporal changes in the dynamics of (small) mammals and their pathogens, their predators and ultimately, how those intertwined dynamics under a context of global change can cascade into zoonotic spillover and outbreaks in humans. Our approach pairs long-term monitoring, cross-biome collaborations and manipulative experiments.