Ubiquitin E3 ligases in plant pathogen responses

In this study, we will establish the role of RING genes in fungal susceptibility using a RING gene knockout collection and Botrytis cinerea as model pathogen, through the high-throughput screening methods developed here. Ultimately, a selection from the 13 RING genes, which are upregulated as a response to B. cinerea infection, will be characterized in detail at molecular level as a proof of concept of the screening method.