Selected publications

Itkonen, S. T., Karhu, P., Pellinen, T., Lehtovirta, M., Kaartinen, N. E., Männistö, S., Päivärinta, E., & Pajari, A-M. (2023). Effects of partial replacement of red and processed meat with non-soya legumes on bone and mineral metabolism and amino acid intakes in BeanMan randomised clinical trial. British Journal of Nutrition, 131(1), 82-91.

DOI: 10.1017/S0007114523001514

Slabá, H., Määttänen, M., Marttinen, M., Lapinkero, V., Päivärinta, E., & Pajari, A. M. (2023). Daily berry consumption attenuates β-catenin signalling and genotoxicity in colon carcinoma cells exposed to faecal water from healthy volunteers in a clinical trial. Journal of Functional Foods, 102, 105440.

DOI: 10.1016/j.jff.2023.105440

Pellinen, T., Päivärinta, E., Isotalo, J., Lehtovirta, M., Itkonen, S. T., Korkalo, L., Erkkola, M. & Pajari, A.-M. (2022). Replacing dietary animal-source proteins with plant-source proteins changes dietary intake and status of vitamins and minerals in healthy adults: a 12-week randomized controlled trial. European Journal of Nutrition, 61, 1391-1404.

DOI: 10.1007/s00394-021-02729-3

Itkonen, S.T., Päivärinta, E., Pellinen, T., Viitakangas, H., Risteli, J., Erkkola, M., Lamberg-Allardt, C., & Pajari, A.-M. (2021). Partial Replacement of Animal Proteins with Plant Proteins for 12 Weeks Accelerates Bone Turnover Among Healthy Adults: A Randomized Clinical Trial. The Journal of Nutrition, 51(1), 11–19.

DOI: 10.1093/jn/nxaa264

Päivärinta, E., Itkonen, S.T., Pellinen, T., Lehtovirta, M., Erkkola, M., & Pajari, A.-M. (2020). Replacing Animal-Based Proteins with Plant-Based Proteins Changes the Composition of a Whole Nordic Diet — A Randomized Clinical Trial in Healthy Finnish Adults. Nutrients, 12, 943.

DOI: 10.3390/nu12040943

Pihlanto A, Mattila P, Mäkinen S, Pajari AM. Bioactivities of alternative protein sources and their potential health benefits. Food & Function 2017;8:3443-3458.

DOI: 10.1039/c7fo00302a

Niku M*, Pajari AM*, Sarantaus L, Päivärinta E, Storvik M, Heiman-Lindh A, Nyström M, Mutanen M. Western diet enhances intestinal tumorigenesis in Min/+ mice, associating with mucosal metabolic and inflammatory stress and loss of Apc heterozygosity. Journal Nutritional Biochemistry 2017;39:126-133.

*Equal contribution to the paper with shared first authorship.

DOI: 10.1016/j.jnutbio.2016.09.016

Päivärinta E, Maukonen J, Niku M, Heiman-Lindh A, Saarela M, Pajari AM, Mutanen M. Changes in intestinal immunity, gut microbiota, and expression of energy metabolism-related genes explain adenoma growth in bilberry and cloudberry-fed Apc Min mice. Nutrition Research 2016;36:1285-1297.

DOI: 10.1016/j.nutres.2016.10.003

Pajari AM, Päivärinta E, Paavolainen L, Vaara E, Koivumäki T, Mutanen M, Marjomäki V, Ridley A. Ellagitannin-rich cloudberry inhibits hepatocyte growth factor-induced cell migration and phosphatidylinositol 3-kinase/AKT activation in colon carcinoma cells and tumors in Min mice. Oncotarget 2016;7:43907-43923.

DOI: 10.18632/oncotarget.9724

Mecklin JP, Malila N, Kääriäinen H, Pajari AM, Färkkilä M. Suolistosyövän riskitekijät ja ehkäisyn mahdollisuudet [Risk factors and possibilities of prevention of bowel cancer]. Duodecim 2016;132:1145-1152.

Link for the article in Finnish

Oostindjer M, Alexander J, Amdama GV, Andersen G, Bryane NS, Chen D, Corpet DE, De Smet D, Dragsted LU, Karlsson AH, Kleter G, de Kok TM, Kulseng B, Milkowski AL, Martino RJ, Pajari AM, Paulsen JE, Pickova J, Rudi K, Sødring M, Weed DL, Egelandsdal B. The role of red and processed meat in colorectal cancer development: a perspective. Meat Science 2014;97:583-596.

DOI: 10.1016/j.meatsci.2014.02.011

Marttinen M, Päivärinta E, Storvik M, Huikko L, Luoma-Halkola H, Piironen V, Pajari AM, Mutanen M. Plant stanols induce intestinal tumor formation by up-regulating Wnt and EGFR signaling in ApcMin mice. Journal of Nutritional Biochemistry 2013;24:343-352.

DOI: 10.1016/j.jnutbio.2012.07.002

Misikangas M*, Pajari AM*, Päivärinta E*, Oikarinen SI, Rajakangas J, Järvinen M, Salminen HK, Törrönen R, Mutanen M. Three Nordic berries inhibit intestinal tumorigenesis in Min/+ mice by modulating ß-catenin signaling in the tumor and transcription in the mucosa. Journal of Nutrition 2007;137:2285-2290.

*Equal contribution to the paper with shared first authorship.

DOI: 10.1093/jn/137.10.2285

Pajari AM, Rajakangas J, Päivärinta E, Kosma VM, Rafter J, Mutanen M. Promotion of intestinal tumor formation by inulin is associated with an accumulation of cytosolic ß-catenin in Min mice. International Journal of Cancer 2003;106:653-660.

DOI: 10.1002/ijc.11270

Mutanen M, Pajari AM, Oikarinen S. Beef induces and rye bran prevents formation of intestinal polyps in APCMin mice: relation to ß-catenin and PKC-isozymes. Carcinogenesis 2000;21:1167-1173.

DOI: 10.1093/carcin/21.6.1167

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