Selected publications

  • Syed S, Viazmina L, Mager R, Meri S, Haapasalo K. Streptococci and the complement system: interplay during infection, inflammation and autoimmunity. FEBS Lett. 2020

  • Meri S and Haapasalo K. Regulation of the complement system by pentraxins. Front. Immunol. 2019.

  • Syed S, Hakala P, Singh AK, Lapatto HAK, King SJ, Meri S, Jokiranta TS, Haapasalo K. Role of Pneumococcal NanA Neuraminidase Activity in Peripheral Blood. Front. Cell. Infect. Microbiol., 26 June 2019 

  • Weldatsadik RG, Datta N, Kolmeder C, Vuopio J, Kere J, Wilkman SV, Flatt JW, Vuento R, Haapasalo KJ, Keskitalo S, Varjosalo M, Jokiranta TS. Pool-seq driven proteogenomic database for Group G Streptococcus. J Proteomics. 2019 Apr 20;201:84-92. doi: 10.1016/j.jprot.2019.04.015. 

  • Haapasalo K, Wollman AJM, de Haas CJC, van Kessel KPM, van Strijp JAG, Leake MC. Staphylococcus aureus toxin LukSF dissociates from its membrane receptor target to enable renewed ligand sequestration. FASEB J. 2019 Mar;33(3):3807-3824. doi: 10.1096/fj.201801910R. Epub 2018 Dec 3.

  • Nissilä E, Hakala P, Leskinen K, Roig A, Syed S, Van Kessel KPM, Metso J, De Haas CJC, Saavalainen P, Meri S, Chroni A, Van Strijp JAG, Öörni K, Jauhiainen M, Jokiranta TS, Haapasalo K. Complement Factor H and Apolipoprotein E Participate in Regulation of Inflammation in THP-1 Macrophages. Front. Immunol. 2018. 

  • Haapasalo K, Koskinen L.L.E., Suvilehto J, Jousilahti P, Wennerström A, Suomela S, Trembath R, Barker J, Vuopio J, Kere J, Jokiranta T.S., Saavalainen P. The psoriasis risk allele HLA-Cw0602 shows evidence of association with chronic or recurrent streptococcal tonsillitis and points to shared T cell epitopes in these diseases. Infect Immun. 2018

  • Nissilä E, Douillard FP, Ritari J, Paulin L, Järvinen HM, Rasinkangas P, Haapasalo K, Meri S, Jarva H,  de Vosa WM. 2017.  Genotypic and Phenotypic Diversity of Lactobacillus rhamnosus Clinical Isolates Compared to Lactobacillus rhamnosus GG and Their Recognition by Complement System. Plos One.
  • Amdahl H, Haapasalo K, Tan L, Meri T, Kuusela PI, van Strijp JA, Rooijakkers S, Jokiranta TS. 2017. Staphylococcal protein Ecb impairs complement receptor-1 mediated recognition of opsonized bacteria. PLoS One.
  • Haapasalo K, van Kessel K, Nissilä E, Metso J, Johansson T, Miettinen S, Varjosalo M, Kirveskari J, Kuusela P, Chroni A, Jauhiainen M, van Strijp J, Jokiranta TS. 2015. Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles. J Biol Chem. 
  • Amdahl H, Jongerius I, Meri T, Pasanen T, Hyvärinen S, Haapasalo K, van Strijp JA, Rooijakkers SH, Jokiranta TS. 2013. Staphylococcal Ecb protein and host complement regulator factor H enhance functions of each other in bacterial immune evasion. J Immunol.
  • Haapasalo K, Vuopio J, Syrjänen J, Suvilehto J, Massinen S, Karppelin M, Järvelä I, Meri S, Kere J, Jokiranta TS. 2012. Acquisition of Complement Factor H Is Important for Pathogenesis of Streptococcus pyogenes Infections: Evidence from Bacterial In Vitro Survival and Human Genetic Association. J. Immunol. (corresponding author)
  • Haapasalo K, Suomalainen P, Sukura A, Siikamäki H, Jokiranta TS. 2010. Babesiosis in Human, Finland, 2004. Em Inf Dis.
  • Haapasalo K, Meri T, Jokiranta TS. 2009. Loa loa Microfilariae evade complement attack in vivo by acquiring regulatory proteins from host plasma. Infect Immun.
  • Haapasalo K, Jarva H, Siljander T, Tewodros W, Vuopio-Varkila J, Jokiranta TS. 2008. Complement factor H allotype 402H is associated with increased C3b opsonization and phagocytosis of Streptococcus pyogenes. Mol Microbiol.
  • Laine M, Jarva H, Seistonen S, Haapasalo K, Lehtinen MJ, Lindeman N, Anderson DH, Johnson PT, Järvelä IT, Jokiranta TS, Hageman GS, Immonen I, Meri S. 2007. Y402H Polymorphism of Complement Factor H Affects Binding Affinity to C-Reactive Protein. J Immunol.