The Explorations of Anti-infectives research (AIR) group has two main research areas; to explore new treatment possibilities against the intracellular pathogen Chlamydia spp. and to study bacterial biofilms and search for novel ways to solve the highly relevant medical problems they cause. In the search for new treatments we mainly focus on solutions based on natural producs and naturally derived substances. We have, for instance, identified active antibiofilm compounds from wood resins and anti-chlamydial compounds from Schisandra lignans.

Professor Pia Vuorela (1961-2017) was successfully leading the Explorations of Anti-infectives research group until she passed away in October 2017.

Malena Skogman is the head of the team studying bacterial biofilms. Here the research is targeting novel ways to conqur infections caused by biofilms, both gram positive (i.e. Staphylococcus aureus, Staphylococcus epidermidis) and gram negative (i.e. Pseudomonas aeruginosa, Burkholderia cenocepacia, Escherichia coli). We have developed an assay platform for screening of compounds for antibiofilm activity using several staining assays. We are also focusing on alternative ways to eradicate and prevent biofilm formation by targeting quorum sensing and persister bacteria. 

Leena Hanski is the head of the team studying infections by the intracellular pathogen Chlamydia pneumoniae. The research is targeting at finding new effective compounds with anti-chlamydial activity, mainly from natural origin. 

We belong to Pharmaceutical Biology at the Division of Pharmaceutical Biosciences, Faculty of Pharmacy. We are also part of the Pharmaceutical Design and Discovery group. 




Moderated by Malena Skogman, 2017