Publications

2023

• Lokki AI, Ren Z, Triebwasser M, Daly E; FINNPEC; Perola M, Auro K, Burwick R, Salmon JE, Daly M, Laivuori H, Atkinson JP, Java A, Meri S. Identification of complement factor H variants that predispose to pre-eclampsia: A genetic and functional study.BJOG. 2023 doi: 10.1111/1471-0528.17529. 
• Chernyaeva L, Ratti G, Teirilä L, Fudo S, Rankka U, Pelkonen A, Korhonen P, Leskinen K, Keskitalo S, Salokas K, Gkolfinopoulou C, Crompton KE, Javanainen M, Happonen L, Varjosalo M, Malm T, Leinonen V, Chroni A, Saavalainen P, Meri S, Kajander T, Wollman AJ, Nissilä E, Haapasalo K. Reduced binding of apoE4 to complement factor H promotes amyloid-β oligomerization and neuroinflammation. EMBO Rep. 2023:e56467. doi: 10.15252/embr.202256467.
• Jiang M, Väisänen E, Kolehmainen P, Huttunen M, Ylä-Herttuala S, Meri S, Österlund P, Julkunen I. COVID-19 adenovirus vector vaccine induces higher interferon and pro-inflammatory responses than mRNA vaccines in human PBMCs, macrophages and moDCs.Vaccine. 2023:S0264-410X(23)00463-2. doi: 10.1016/j.vaccine.2023.04.049.
• Freitag TL, Fagerlund R, Karam NL, Leppänen VM, Ugurlu H, Kant R, Mäkinen P, Tawfek A, Jha SK, Strandin T, Leskinen K, Hepojoki J, Kesti T, Kareinen L, Kuivanen S, Koivulehto E, Sormunen A, Laidinen S, Khattab A, Saavalainen P, Meri S, Kipar A, Sironen T, Vapalahti O, Alitalo K, Ylä-Herttuala S, Saksela K. Intranasal administration of adenoviral vaccines expressing SARS-CoV-2 spike protein improves vaccine immunity in mouse models.Vaccine. 2023;41(20):3233-3246. doi: 10.1016/j.vaccine.2023.04.020.
• Kalantar K, Ghamar Talepoor A, Eshkevar Vakili M, Karami N, Kalani M, Ghandehari F, Kabelitz D, Meri S, Moattari A. Th-1, Th-2, Th-9, Th-17, Th-22 type cytokine concentrations of critical COVID-19 patients after treatment with Remdesivir. Immunobiology. 2023;228(3):152378. doi: 10.1016/j.imbio.2023.152378.
• Karimi S, Mehdipour F, Sarvari J, Ataollahi MR, Ramezani A, Meri S, Kalantar K. Investigation of the frequencies of various B cell populations in non-responder healthcare workers in comparison with responders to hepatitis B virus vaccination. Trans R Soc Trop Med Hyg. 2023:trad016. doi: 10.1093/trstmh/trad016.
• Sipilä PN, Lindbohm JV, Batty GD, Heikkilä N, Vahtera J, Suominen S, Väänänen A, Koskinen A, Nyberg ST, Meri S, Pentti J, Warren-Gash C, Hayward AC, Kivimäki M. Severe Infection and Risk of Cardiovascular Disease: A Multicohort Study.Circulation. 2023;147(21):1582-1593. doi: 10.1161/CIRCULATIONAHA.122.061183.
• Kovala M, Seppälä M, Räisänen-Sokolowski A, Meri S, Honkanen E, Kaartinen K. Diagnostic and Prognostic Comparison of Immune-Complex-Mediated Membranoproliferative Glomerulonephritis and C3 Glomerulopathy.Cells. 2023;12(5):712. doi: 10.3390/cells12050712.PMID: 36899849.
• Nasrollahi H, Talepoor AG, Saleh Z, Eshkevar Vakili M, Heydarinezhad P, Karami N, Noroozi M, Meri S, Kalantar K. Immune responses in mildly versus critically ill COVID-19 patients. Front Immunol. 2023;14:1077236. doi: 10.3389/fimmu.2023.1077236.

• 2022

• Poppelaars F*, Gaya da Costa M*, Lokki AI*, Mallah K*, Nord D*, Reddaway J*, Schäfer N.* Early-Career Complementologists (ECCO) - Past achievements and future directions. Mol Immunol. 2022 Nov;151:158-165. doi: 10.1016/j.molimm.2022.08.012.
• Rahmati Nezhad P, Riihilä P, Knuutila JS, Viiklepp K, Peltonen S, Kallajoki M, Meri S, Nissinen L, Kähäri VM. Complement Factor D Is a Novel Biomarker and Putative Therapeutic Target in Cutaneous Squamous Cell Carcinoma. Cancers (Basel). 2022, 14(2):305. doi: 10.3390/cancers14020305.
• Leimi L, Jahnukainen K, Olkinuora H, Meri S, Vettenranta K. Early vascular toxicity after pediatric allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2022, doi: 10.1038/s41409-022-01607-8.
• Livson S, Virtanen S, Lokki AI, Holster T, Rahkonen L, Kalliala I, Nieminen P, Salonen A, Meri S. Cervicovaginal Complement Activation and Microbiota During Pregnancy and in Parturition. Front Immunol. 2022 Jul 25;13:925630. doi: 10.3389/fimmu.2022.925630.
• Kovala M, Seppälä M, Kaartinen K, Meri S, Honkanen E, Räisänen-Sokolowski A. Vascular Occlusion in Kidney Biopsy Is Characteristic of Clinically Manifesting Thrombotic Microangiopathy. J Clin Med. 2022;11:3124.
• Dijkstra DJ, Lokki AI, Gierman LM, Borggreven NV, van der Keur C, Eikmans M, Gelderman KA, Laivuori H; FINNPEC Core Investigator Group, Iversen AC, van der Hoorn MP, Trouw LA. Circulating Levels of Anti-C1q and Anti-Factor H Autoantibodies and Their Targets in Normal Pregnancy and Preeclampsia. Front Immunol. 2022 Mar 31;13:842451. doi: 10.3389/fimmu.2022.842451.
• Poppelaars F*, Gaya da Costa M*, Lokki AI*, Mallah K*, Nord D*, Reddaway J*, Schäfer N.* ECCO - A new initiative to support early-career researchers in the complement field. Mol. immunol 2022 Jan;141:104-107. doi: 10.1016/j.molimm.2021.11.018.
• Obach D, Solastie A, Liedes O, Vara S, Krzyżewska-Dudek E, Brinkmann L, Haveri A, Hammer CC, Dub T, Meri S, Freitag TL, Lyytikäinen O, Melin M. Impaired immunity and high attack rates caused by SARS-CoV-2 variants among vaccinated long-term care facility residents. Immun Inflamm Dis. 2022 Sep;10(9):e679. doi: 10.1002/iid3.679. 
• Khattab A, Rezola M, Barroso M, Kyrklund M, Pihlajamaa T, Freitag TL, van Gemert GJ, Bousema T, Permi P, Turunen O, Sauerwein R, Luty AJF, Meri S. Hijacking the human complement inhibitor C4b-binding protein by the sporozoite stage of the Plasmodium falciparum parasite. Front Immunol. 13:1051161, 2022.
• Starck L, Meri S. Immunsvaret mot coronavirus, Finska Läkaresällskapets Handlingar 182, 2:48-53, 2022
• Krzyżewska-Dudek E, Kotimaa J, Kapczyńska K, Rybka J, Meri S. Lipopolysaccharides and outer membrane proteins as main structures involved in complement evasion strategies of non-typhoidal Salmonella strains. Mol Immunol. 2022 Oct;150:67-77. doi: 10.1016/j.molimm.2022.08.009. Epub 2022 Aug 20. PMID: 35998438.
• Meri S, Bunjes D, Cofiell R, Jodele S. The role of complement in HSCT-TMA: basic science to clinical practice. Adv Ther. 2022  doi: 10.1007/s12325-022-02184-4.
• Józsi M, Barlow PN, Meri S. Function and Dysfunction of Complement Factor H Front Immunol. 2022, 12:831044. doi: 10.3389/fimmu.2021.831044.

• 2021

• Pitkänen HH, Jouppila A, Helin T, Dulipati V, Kotimaa J, Meri S, Kantele A, Jalkanen P, Julkunen I, Lassila R. COVID-19 adenovirus vaccine triggers antibodies against PF4 complexes to activate complement and platelets. Thromb Res. 2021, 208:129-137. doi: 10.1016/j.thromres.2021.10.027
• Viiklepp K, Nissinen L, Ojalill M, Riihilä P, Kallajoki M, Meri S, Heino J, Kähäri VM, C1r Upregulates Production of Matrix Metalloproteinase-13 and Promotes Invasion of Cutaneous Squamous Cell Carcinoma, J Invest Dermatol, 2021. :S0022-202X(21)02379-4. doi: 10.1016/j.jid.2021.10.008.
• Kant R†, Kareinen L†, Smura T, Freitag TL, Jha SK, Alitalo K, Meri S, Sironen T, Saksela K, Strandin T, Kipar A, Vapalahti O. Common laboratory mice are susceptible to infection with the SARS-CoV-2 beta variant. Viruses, 2021, 13(11):2263. doi: 10.3390/v13112263
• Bemani P, Eklund KK, Ali-Hassanzadeh M, Kabelitz D, Schmidt RE, Meri S, Kalantar K. Proportion of T follicular helper cells in peripheral blood of rheumatoid arthritis patients: a systematic review and meta-analysis. Expert Rev Clin Immunol. 2021 Apr 15:1-14. doi: 10.1080/1744666X.2021.1915770.
• Johansson NG, Dreano L, Vidilaseris K, Khattab A, Liu J, Lasbleiz A, Ribeiro O, Kiriazis A, Boije Af Gennäs G, Meri S, Goldman A, Yli-Kauhaluoma J, Xhaard H. Exploration of Pyrazolo[1,5-a]pyrimidines as Membrane-Bound Pyrophosphatase Inhibitors. ChemMedChem. 2021 Aug doi: 10.1002/cmdc.202100392
• Syed S, Nissilä E, Ruhanen H, Fudo S, Gaytán MO, Sihvo SP, Lorey MB, Metso J, Öörni K, King SJ, Oommen OP, Jauhiainen M, Meri S, Käkelä R, Haapasalo K. Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles. iScience. 2021 May 12;24(6):102535. doi: 10.1016/j.isci.2021
• Kelly CP, Murray JA, Leffler DA, Getts DR, Bledsoe AC, Smithson G, First MR, Morris A, Boyne M, Elhofy A, Wu TT, Podojil JR, Miller SD. TAK-101 Nanoparticles Induce Gluten-Specific Tolerance in Celiac Disease: A Randomized, Double-Blind, Placebo-Controlled Study. TAK-101 Study Group. Gastroenterology. 2021 Jul;161(1):66-80.e8. doi: 10.1053/j.gastro.2021.03.014.
• Vuorela A*, Freitag T*, Leskinen K, Pessa H, Härkönen T, Stracenski I, Kirjavainen T, Olsen P, Saarenpää-Heikkilä O, Ilonen J , Knip M, Vaheri A, Partinen M, Saavalainen P, Meri S*, Vaarala O*. Enhanced influenza A H1N1 T cell epitope recognition and cross-reactivity to protein-O-mannosyltransferase 1 in Pandemrix-associated narcolepsy type 1.Nature Communications, 2021;12(1):2283. doi: 10.1038/s41467-021-22637-8.
• Lokki AI, Teirilä L, Triebwasser M, Daly E, Bhattacharjee A, Uotila L, Llort Asens M, Kurki MI, Perola M, Auro K, Salmon JE, Daly M, Atkinson JP, Laivuori H, Fagerholm S, Meri S; Finnpec. Dysfunction of complement receptors CR3 (CD11b/18) and CR4 (CD11c/18) in pre-eclampsia: a genetic and functional study. BJOG. 2021 Feb 4. doi: 10.1111/1471-0528.16660.
• Rahmati Nezhad P, Riihilä P, Piipponen M, Kallajoki M, Meri S, Nissinen L, Kähäri VM. Complement Factor I upregulates expression of matrix metalloproteinase-13 and -2 and promotes invasion of cutaneous squamous carcinoma cells. Exp Dermatol. 2021 Apr 4. doi: 10.1111/exd.14349.
• Ortín-Piqueras V, Freitag TL, Andersson LC, Lehtonen SH, Meri SK, Spillmann T, Frias R Urinary Excretion of Iohexol as a Permeability Marker in a Mouse Model of Intestinal Inflammation: Time Course, Performance and Welfare Considerations.Animals (Basel). 2021;11(1):79. doi: 10.3390/ani11010079.

• 2020

• Kaartinen K, Martola L, Aaltonen S, Meri S. Diagnostic Dilemma of Thrombotic Microangiopathy in Pregnancy. Kidney Int Rep. 2020;6(2):529-533. doi: 10.1016/j.ekir.2020.10.036..PMID: 33615079.
• 274. Livson S, Jarva H, Kalliala I, Lokki AI, Heikkinen-Eloranta J, Nieminen P, Meri S. Activation of the Complement System in the Lower Genital Tract During Pregnancy and Delivery. Front Immunol. 2021 Jan 11;11:563073. doi: 10.3389/fimmu.2020.563073
• Ortín-Piqueras V, Freitag TL, Andersson LC, Lehtonen SH, Meri SK, Spillmann T, Frias R Urinary Excretion of Iohexol as a Permeability Marker in a Mouse Model of Intestinal Inflammation: Time Course, Performance and Welfare Considerations. Animals (Basel). 2021;11(1):79. doi: 10.3390/ani11010079.
• Freitag TL*, Podojil JR*, Pearson RM, Fokta FJ, Sahl C, Messing M, Andersson LC, Leskinen K, Saavalainen P, Hoover LI, Huang K, Phippard D, Maleki S, King NCJ, Shea LD, Miller SD, Meri S, Getts DR. Gliadin nanoparticles induce immune tolerance to gliadin in mouse models of celiac disease. Gastroenterology 2020; 158:1667-1681
• Melén K, Jalkanen P, Kukkonen JP, Partinen M, Nohynek H, Vuorela A, Vaarala O, Freitag TL, Meri S, Julkunen IJ. No evidence of autoimmunity to human OX1 or OX2 orexin receptors in Pandemrix-vaccinated narcoleptic children. Transl Autoimmun. 2020, 3:100055. doi: 10.1016/j.jtauto.2020.100055. eCollection 2020.PMID: 32743535
• Reichhardt M, Messing M, Andersson S, Kolho KL, Meri S. SALSA/dmbt1 levels are decreased in prematurely born infants. Scand J Immunol, 2020; 93(2):e12987. doi: 10.1111/sji.12987.
• Meri S, Haapasalo K. Function and dysfunction of complement factor H during formation of lipid-rich deposits. Front Immunol. 2020 doi: 10.3389/fimmu.2020.611830
• Daryabor G, Atashzar MR, Kabelitz D, Meri S, Kalantar K. The Effects of Type 2 Diabetes Mellitus on Organ Metabolism and the Immune System. Front Immunol. 2020 Jul 22;11:1582. doi: 10.3389/fimmu.2020.01582. eCollection 2020.PMID: 3279322
• Complement evasion strategies of Borrelia burgdorferi sensu lato Dulipati, V., Meri, S. and Panelius, J. FEBS Lett, 594: 2645-2656. 8.2020
• Complement in malaria: immune evasion strategies and role in protective immunity Kiyuka PK, Meri S, Khattab A. FEBS Lett. 2020 Mar 17. 17.3.2020
• Physiology of gangliosides and the role of antiganglioside antibodies in human diseases Cutillo G, Saariaho AH, Meri S. Cell Mol Immunol. 2020 Mar 9. 9.3.2020
• Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease Freitag TL, Podojil JR, Pearson RM, Fokta FJ, Sahl C, Messing M, Andersson LC, Leskinen K, Saavalainen P, Hoover LI, Huang K, Phippard D, Maleki S, King NJC, Shea LD, Miller SD, Meri SK, Getts DR. Gastroenterology. 2020 Feb 4. 4.2.2020

2019

• Minor Effect of Antibiotic Pre-treatment on the Engraftment of Donor Microbiota in Fecal Transplantation in Mice Freitag TL, Hartikainen A, Jouhten H, Sahl C, Meri S, Anttila VJ, Mattila E, Arkkila P, Jalanka J, Satokari R. Front Microbiol. 2019 Nov 21;10:2685. 21.11.2019

• Regulation of the complement system and immunological tolerance in pregnancy Teirilä L, Heikkinen-Eloranta J, Kotimaa J, Meri S, Lokki AI. Semin Immunol. 2019 Oct;45:101337. 10.2019

• Complement dysregulation in glomerulonephritis Kaartinen K, Safa A, Kotha S, Ratti G, Meri S. Semin Immunol. 2019 Oct;45:101331. 10.2019
• Disturbances in complement recognition and control in human disease - An editorial to a special issue on "Complement Regulation" Meri S. Semin Immunol. 2019 Oct;45:101345. 10.2019
• Complement in Human Pre-implantation Embryos: Attack and Defense Reichhardt MP, Lundin K, Lokki AI, Recher G, Vuoristo S, Katayama S, Tapanainen JS, Kere J, Meri S, Tuuri T. Front Immunol. 2019 Sep 18;10:2234. 18.9.2019
• Regulation of the Complement System by Pentraxins Haapasalo K, Meri S. Front Immunol. 2019 Aug 2;10:1750. 2.8.2019
• Role of Pneumococcal NanA Neuraminidase Activity in Peripheral Blood Syed S, Hakala P, Singh AK, Lapatto HAK, King SJ, Meri S, Jokiranta TS, Haapasalo K. Front Cell Infect Microbiol. 2019 Jun 26;9:218. 26.6.2019
• Asymmetry in catalysis by Thermotoga maritima membrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor Vidilaseris K, Kiriazis A, Turku A, Khattab A, Johansson NG, Leino TO, Kiuru PS, Boije Af Gennäs G, Meri S, Yli-Kauhaluoma J, Xhaard H, Goldman A. Sci Adv. 2019 May 22;5(5):eaav7574. 22.5.2019

2018

• Complement Factor H and Apolipoprotein E Participate in Regulation of Inflammation in THP-1 Macrophages Nissilä, E., Hakala, P., Leskinen, K., Roig, A., Syed, S., Van Kessel, K. P. M., Metso, J., De Haas, C. J. C., Saavalainen, P., Meri, S., Chroni, A., Van Strijp, J. A. G., Öörni, K., Jauhiainen, M., Jokiranta, T. S. & Haapasalo, K., 21 Nov 2018, In : Frontiers in Immunology. 9, 14 p., 2701 21.11.2018
• The Immunogenetic Conundrum of Preeclampsia Lokki, A. I., Heikkinen-Eloranta, J. K. & Laivuori, H., 13 Nov 2018, In : Frontiers in Immunology. 9, 8 p., 2630. 13.11.2018
• Spontaneous Remission in Paroxysmal Nocturnal Hemoglobinuria—Return to Health or Transition Into Malignancy? Korkama, E-S., Armstrong, A-E., Jarva, H. & Meri, S., 2 Aug 2018, In : Frontiers in Immunology. 9, 5 p., 1749. 2.8.2018

2017

• SALSA-A dance on a slippery floor with changing partners Reichhardt, M. P., Holmskov, U. & Meri, S., Sep 2017, In : Molecular Immunology. 89, p. 100-110 11 p. 1.9.2017
• 3D mosquito screens to create window double screen traps for mosquito control Khattab, A., Jylha, K., Hakala, T., Aalto, M., Malima, R., Kisinza, W., Honkala, M., Nousiainen, P. & Meri, S., 29 Aug 2017, In : Parasites & vectors. 10, 12 p., 400. 29.8.2017

2016

• The alternative pathway of complement Meri, S., 2016, Encyclopedia of Immunobiology. Ratcliffe, M. J. H. (ed.). 1st ed. ed. Academic Press, p. 325-331 7 p.
• The Salivary Scavenger and Agglutinin (SALSA) in Healthy and Complicated Pregnancy Reichhardt, M. P., Jarva, H., Lokki, A. I., Laivuori, H., Vuorela, P., Loimaranta, V., Glasner, A., Siwetz, M., Huppertz, B., Meri, S. & FINNPEC Study Grp, 1 Feb 2016, In : PLoS One. 11, 2, 19 p., 0147867. 1.2.2016

2015

• Autoantibodies against ganglioside GM3 are associated with narcolepsy-cataplexy developing after Pandemrix vaccination against 2009 pandemic H1N1 type influenza virus Saariaho, A-H., Vuorela, A., Freitag, T. L., Pizza, F., Plazzi, G., Partinen, M., Vaarala, O. & Meri, S., Sep 2015, In : Journal of Autoimmunity. 63, p. 68-75 8 p. 1.9.2015
• Dysregulation of adaptive immune responses in complement C3-deficient patients Pekkarinen, P. T., Heikkila, N., Kisand, K., Peterson, P., Botto, M., Daha, M. R., Drouet, C., Isaac, L., Helminen, M., Haahtela, T., Meri, S., Jarva, H. & Arstila, T. P., Mar 2015, In : European Journal of Immunology. 45, 3, p. 915-921 7 p. 1.3.2015
• Anopheles Midgut Epithelium Evades Human Complement Activity by Capturing Factor H from the Blood Meal Khattab, A., Barroso, M., Miettinen, T. & Meri, S., Feb 2015, In : PLoS Neglected Tropical Diseases. 9, 2, 23 p., 0003513. 13.2.2015

2014

• Complement activation and regulation in preeclamptic placenta Lokki, A. I., Heikkinen-Eloranta, J., Jarva, H., Saisto, T., Lokki, M-L., Laivuori, H. & Meri, S., 2014, In : Frontiers in Immunology. 5, p. 1-14 14 p., 312. 1.7.2014
• Complement C4 Deficiency - A Plausible Risk Factor for Non-Tuberculous Mycobacteria (NTM) Infection in Apparently Immunocompetent Patients Kotilainen, H., Lokki, M-L., Paakkanen, R., Seppanen, M., Tukiainen, P., Meri, S., Poussa, T., Eskola, J., Valtonen, V. & Jarvinen, A., 17 Mar 2014, In : PLoS One. 9, 3, 6 p., 91450. 17.3.2014

2013

• Complement activation in diseases presenting with thrombotic microangiopathy. Meri S. Eur J Int Med, S0953-6205(13)00137-4, 2013 1.9.2013
• Microbes bind complement inhibitor factor H via a common site. Meri T, Amdahl H, Lehtinen MJ, Hyvärinen S, McDowell JV, Bhattacharjee A, Meri S, Marconi R, Goldman A, Jokiranta TS. PLOS Pathogens 9(4) e1003308, 2013 18.4.2013
• Impaired intestinal tolerance in the absence of a functional complement system. Pekkarinen PT, Vaali K, Jarva H, Kekäläinen E, Hetemäki I, Junnikkala S, Helminen M, Vaarala O, Meri S, Arstila TP. J Allergy Clin Immunol, 131(4):1167-75, 2013 1.4.2013

2012

• Opc expression, LPS immunotype switch and pilin conversion contribute to serum resistance of unencapsulated meningococci. Hubert K, Pawlik MC, Claus H, Jarva H, Meri S, Vogel U.PLoS One. 7(9):e45132, 2012 20.9.2012
• The salivary scavenger and agglutinin binds MBL and regulates the lectin pathway of complement in solution and on surfaces. Reichhardt MP, Loimaranta V, Thiel S, Finne J, Meri S, Jarva H. Front Immunol. 3:205, 2012 16.7.2012
• Functional recruitment of the human complement inhibitor C4BP to Yersinia pseudotuberculosis outer membrane protein Ail. Ho DK, Riva R, Kirjavainen V, Jarva H, Ginström E, Blom AM, Skurnik M, Meri S. J Immunol. 188:4450-9, 2012 1.5.2012
• Complement lectin pathway genotypes associated with placental malaria. Holmberg V, Onkamo P, Lahtela E, Lahermo P, Bedu-Addo G, Mockenhaupt F, Meri S. Malaria J. 11; 61, 2012 2.3.2012

2011

• Molecular identification of Taenia spp. in wolves (Canis lupus), brown bears (Ursus arctos) and cervids from North Europe and Alaska. Lavikainen A, Laaksonen S, Beckmen K, Oksanen A, Isomursu M, Meri S. Parasitol Int. 60:289-95, 2011 1.9.2011
• Exposure of the Plasmodium falciparum clonally variant STEVOR proteins on the merozoite surface. Khattab A, Meri S. Malar J, 10: 58, 2011 14.3.2011

2010

• Lack of complement inhibitors in the outer intracranial artery aneurysm wall associates with complement terminal pathway activation. Tulamo R, Frösen J, Paetau A, Seitsonen S, Hernesniemi J, Niemelä M, Järvelä I, Meri S. Am. J Pathol, 177:3224-32, 2010 1.12.2010
• Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement. Kajander T, Lehtinen MJ, Hyvärinen S, Bhattacharjee A, Leung E, Isenman DE, Meri S, Goldman A, Jokiranta TS. Proc Natl Acad Sci USA, 108: 2897-902, 2011 5.1.2010
• Human complement factor H binds to outer membrane protein Rck of Salmonella. Ho DK, Jarva H, Meri S. J Immunol. 185:1763-9, 2010 1.8.2010

Older

• Yersinia enterocolitica serum resistance proteins YadA and Ail bind the complement regulator C4b-binding protein. Kirjavainen V, Jarva H, Biedzka-Sarek M, Blom A, Skurnik M, Meri S. PLOS Pathogens, 2008 29.8.2008
• Y402H polymorphism of complement factor H affects binding affinity to C-reactive protein. Laine M, Jarva H, Seitsonen S, Haapasalo K, Lehtinen MJ, Lindeman N, Anderson DH, Johnson PT, Järvelä I, Jokiranta TS, Hageman GS, Immonen I and Meri S. J Immunol, 178:3831-6, 2007 15.3.2007
• Binding of the complement inhibitor C4bp to serogroup B Neisseria meningitidis. Jarva H, Ram S, Vogel U, Blom AM, Meri S. J Immunol, 174:6299-6307, 2005 15.5.2005
• The group B streptococcal beta and pneumococcal Hic proteins are structurally related immune evasion molecules that bind the complement inhibitor factor H in an analogous fashion. Jarva H, Hellwage J, Jokiranta TS, Lehtinen M, Zipfel PF, Meri S. J Immunol, 172: 3111-8, 2004 1.3.2004
• Recognition of complement C3b/C3d and cell surface polyanions by overlapping binding sites on the most carboxy-terminal domain 20 of complement factor H. Hellwage J, Jokiranta TS, Friese MA, Wolk TU, Kampen E, Zipfel PF, Meri S. J Immunol, 169:6935-44, 2002 15.12.2002
• Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs. Alitalo A, Meri T, Lankinen H, Seppälä IJT, Lahdenne P, Hefty PS, Akins D & Meri S. J Immunol, 169: 3847-53, 2002 1.10.2002