Our project investigates how the remarkable variation in head morphology across vertebrates—especially among reptiles—is shaped by both ecological factors and underlying developmental mechanisms. We focus in particular on squamate reptiles (lizards and snakes), which offer an extraordinary—but still underexplored—diversity in craniofacial form, lifestyle, and evolutionary innovation.
We approach this research from two complementary angles:
1. Ecomorphological integration of form and function:
We explore how craniofacial morphology is shaped by ecological and behavioral demands. Squamates, with their wide range of feeding strategies, locomotor modes, and habitat use, are ideal for examining how head shape relates to function in an evolutionary context. Using high-resolution 3D imaging (X-ray microcomputed tomography, soft tissue contrast enhancement, cinematic rendering), we reconstruct craniofacial structures in fine detail. We apply geometric morphometrics and advanced statistical analyses to quantify shape variation and identify patterns associated with ecological adaptation.
2. Developmental mechanisms of craniofacial patterning:
Despite the importance of the craniofacial region in both evolution and human health, our understanding of the developmental processes underlying its diversity is still limited—especially beyond traditional model organisms. We address this gap by integrating molecular and developmental biology approaches in emerging reptile models. By combining molecular, imaging, multi-omics, and functional data, we investigate the gene regulatory networks, signaling pathways, and cellular dynamics that drive craniofacial development. Our goal is to identify how developmental programs are modified across species to produce novel forms, and how these changes align with ecological transitions.
By bridging the gap between ecological function and developmental origin, this project aims to uncover how complex craniofacial traits evolve. Ultimately, our findings will contribute to a broader understanding of vertebrate diversity, inform models of evolutionary innovation, and provide new perspectives on craniofacial developmental disorders.
Additional information can be found in our recent publications (see Publication Page).