People

Researchers working in the Andressoo group.

JOA group

 

We are always looking for highly motivated and skilled colleagues. Ideal candidates should have a background in molecular biology and/or animal models.  In particular, we look for expertise in CRISPR-Cas9-related techniques, in proteostasis, mitochondrial and/or neurotrophic functionality, in cell and developmental biology and in mouse and zebrafish models. We are also considering adding the C. elegans model to our toolkit.

If you are interested in a position at any level, please send a cover letter explaining your motivation, CV and the names of two or more references to jaan-olle.andressoo@helsinki.fi.

Principal Investigator

I am fascinated by how regulation of gene expression affects complex phenotypes such as development and aging. I find particularly interesting how gene untranslated regions (UTRs) mediate regulatory processes such as microRNA binding, and whether targeted alterations of them can lead to scientific and therapeutic advances. Specifically, I aim to develop tools allowing control of endogenous morphogen expression to treat neurodegenerative diseases. I believe that the ability to regulate endogenous gene expression has enormous scientific and therapeutic potential.

My favorite free time activities are sea kayaking and drumming, not to mention fishing and different kinds of indoor and outdoor sports.

 

PhD student

I graduated from Columbia University in 2016 where I majored in Neuroscience with a special concentration in Linguistics. During my studies at Columbia University, I spent 4 years working in Professor David Sulzer's lab, specializing in amphetamine pharmacology and autophagy. Upon graduation, I began my academic career in Helsinki as I completed 1 year of supervised, independent research with Jaan-Olle Andressoo's group after being awarded a Fulbright scholarship. Now, as I continue my research in the Andressoo group, my interests focus on neurotrophic factors, and how they modulate the basic biological underpinnings of neuronal function.

daniel.garton@helsinki.fi

 

PhD student

I graduated in Pharmacy and Pharmaceutical Chemistry at the University of Novara, Italy, in 2015. I carried out my Master's thesis project at the University of Helsinki, and after that I continued my research investigating the molecular mechanisms, in particular microRNAs, involved in the altered brain-derived neurotrophic factor (BDNF) signaling in fragile X syndrome. I joined Andressoo’s group in 2017, and my studies focus on enhancing mitochondrial function and endogenous glial cell-derived neurotrophic factor (GDNF) levels to modulate Parkinson’s disease progression and motor coordination.

giorgio.turconi@helsinki.fi

PhD student

I received my B.Sc. degree in biology from the National Autonomous University of Mexico (UNAM) in 2013. During my B.Sc. studies I specialized in developmental biology and genetics, and developed my thesis on dietary antimutagenic compounds at the Antimutagenesis and Antiteratogenesis Lab in the same University. In 2017 I obtained the M.Sc. in Neuroscience from the University of Helsinki. I carried out my master's thesis on an Alzheimer's disease project at the Henri Huttunen lab, where I studied the effects of a circulating peptide on the growth and viability of primary neurons. I joind Andressoo's lab in 2017, where I have recently started my PhD project on the development of tools to regulate endogenous gene expression at the post-transcriptional level. My main scientific interest is to understand better the molecular, cellular and genetic bases of neurodegenerative diseases and to contribute to develop more effective ways to treat them.

ana.montado-rodriguez@helsinki.fi

PhD student

I started my PhD in 2019. I have a Master degree in Pharmacology from the University of Helsinki. I completed my undergraduate degree in Pharmacy in 2016. In Jaan-Olle Andressoo’s lab, I have been studying a GFRA1 hypomorph mouse model and its Hirschsprung’s-disease-related phenotypes.

heikki.t.virtanen@helsinki.fi

Research Assistant

I graduated with a BSc (Hons) in Pharmacology from University College Dublin (UCD) in 2018. Following this I graduated with an MSc in Neuroscience from Trinity College Dublin, where my research was focused on the development of novel therapeutics for neonatal demyelinating disorder, Krabbes disease. Upon completion of my masters, I joined Jaan-Olle Andressoo’s lab where I hope to combine the knowledge gained from my two degrees to further my passion and interest in neuropharmacology. My primary interests lie in research associated with the development of new therapeutics for neurological and psychiatric disorders. My studies with Jaan-Olle Andressoo’s group will initially focus on the role of GDNF in Schizophrenia in hopes to further understand the underlying mechanisms of the disease. 

laoise_casserly@hotmail.com

Student

I am a molecular biosciences student at the University of Helsinki. During my B.Sc. studies I have developed a deep interest in Genetics which will also be the focus of my master’s programme. In addition to my studies in molecular biology I also have a previous background in Chemistry. In Genetics, I am fascinated by the underlying molecular mechanisms that make regulation of gene expression possible. In the spring of 2018 I got the opportunity to join Jaan-Olle’s group and enthusiastically look forward to the times to come.

sakari.hietanen@helsinki.fi

Lab coordinator

I received my Master's degree in genetics from the University of Helsinki in 2018 and before that I received a Bachelor's degree in laboratory sciences from the Metropolia University of Applied Sciences in 2011. I’ve been working in different research groups as a research technician and research assistant since then. Currently I’m the laboratory coordinator of the Andressoo group.

jenni.j.lahtinen@helsinki.fi

Postdocs

Nadine Schweizer, PhD, now National contact person for Horizon 2020 for life sciences and bioeconomy, Sweden

Mugen Terzioglu, PhD, now senior researcher at University of Tampere, Finland

 

PhD students

Lauriina Porokuokka, PhD 2020

Kärt Mätlik, PhD 2018, now postdoctoral researcher at The Rockefeller University, New York, USA

Carolina Vilenius, changed career

Jaakko Kopra, PhD 2016, now Medical Advisor at AbbVie, Finland

Anmol Kumar, PhD 2014, now postdoctoral researcher at Folkhälsan, UH, Finland

Anu Planken, PhD 2011 (co-supervisor)

 

MSc students

Ilaria Morassut, now undergraduate internship at University of Vienna, Austria

Mark Cowlishaw

Rana Mabrouk, now PhD student at University of Eastern Finland

Dipabarna Bhattacharya, now PhD student at Biomedicum, UH, Finland

Soophie Olfat, now Research Assistant at Karolinska Institute, Sweden

 

Soophie Olfat, Research Assistant

Sandra Gellhaar, Postdoctoral Researcher (80%)

Erika Bereczki, Assistant Professor (50%)

Anastasius Damdimopoulos, Bioinformatician (25%)

Topics: gene regulation, ADHD, mouse models, Alzheimer’s disease