The 9th Finnish Symposium on Biological Psychiatry will gather students, researchers, and professionals in the field to discuss the latest advances in psychiatric research. This one-day event promises to be an exciting opportunity for networking, learning, and exploring cutting-edge topics in biological psychiatry.
Keynote Lecture by Prof. Nils B. Kroemer: ‘A critical evaluation of vagus nerve stimulation in biological psychiatry‘
neuroMADLAB – Neuroscience of Motivation, Action, and Desire Laboratory, Department of Psychiatry & Psychotherapy, University of Bonn & Tübingen, Germany
This symposium is aimed at students, postdocs, professionals, and faculty working on:
Don’t miss this opportunity to engage with experts in the field and share your research!
Abstract submission deadline: 15.11.2024
We welcome abstract submissions for short talks.
If you are interested in becoming a sponsor, please contact:
Annette Horstmann
Associate Professor of Behavioural and Brain Sciences
Department of Psychology, University of Helsinki
Organizing Committee:
Iiris Hovatta, Professor of Behavioural Genetics
Tiina Paunio, Professor of Psychiatry
Annette Horstmann, Associate Professor of Behavioural and Brain Sciences
Dr. Luana Colloca is an Mpower Distinguished professor and the Director of the Placebo Beyond Opinion Center at the University of Maryland, School of Nursing, Baltimore. Dr. Colloca holds an MD, a master’s degree in Bioethics and a PhD in Neuroscience. She completed her post-doc training at the Karolinska Institute in Stockholm, Sweden and a senior research fellowship at the National Institutes of Health in Bethesda, USA. Over the last few decades, Dr. Colloca conducted studies on the behavioral, neural, and pharmacological mechanisms of pain modulation related to placebo and nocebo effects. Her lab has also developed an interest in virtual reality as a non-pharmacological approach to relieve pain and other symptoms. She has published in top-ranked international journals including Biological Psychiatry, Annual Reviews of Pharmacology and Toxicology, Nature Review of Rheumatology, Pain, Nature Neuroscience, JAMA, Lancet Neurology, Science and NEJM. Her research has been cited over 17730 times (H-index 62) and featured on The National Geographic, The New Scientist, Washington Post, Science daily, Boston Globe, The New Yorker, Nature, The Guardian, The Wall Street Journal, News and World Reports and USA Today among others. She is committed to science dissemination and this includes podcasts including one with Jason Alexander (Seinfeld), a TEDx talk, and an open-access book with Oxford University Press.
https://www.ted.com/talks/luana_colloca_are_placebos_the_solution
https://academic.oup.com/book/54240
LECTURE 18.9.2024 SLIDES
09.15-09.30 Opening session
09.30-10.30 Caroline Menard, University of Laval: Neurovascular adaptations and biomarkers underlie stress vulnerability vs resilience in mice and human depression.
10.30-11.00 Coffee break
11.00-12.00 Juan Nacher, University of Valencia: Impact of early life adversity on neural circuits and vulnerability to psychiatric disorders.
12.00-13.30 Lunch break (Salad buffet)
13.30-14.30 Alexander Surget, University of Tours: The functional role of adult neurogenesis in shaping hippocampus-dependent functions, stress response and depression-like behaviors - a neurobiological and computational perspective.
14.30-15.30 Iiris Hovatta, University of Helsinki Myelin plasticity in chronic stress and anxiety.
15.30-16.00 Coffee
09.00-10.00 Heidi Taipale, Karolinska Institutet and University of Eastern Finland:
Real-world effectiveness of pharmacotherapies for psychotic depression.
10.00-11.00 Siegfried Kasper, Medical University of Vienna: Recent advances in treatment resistant depression (TRD)
11.00-11.30 Coffee break
11.30-12.30 Marc Hebert, University of Laval: The Eye: An Accessible Window to the Brain for Investigating Biomarkers in Mental Health
12.30 Closing session
For welcoming the new academic year, SleepWell program's 8 groups gathered in Athena hall, UH central campus 5th September 2023. After a nice wake-up mobility session from UniSport, we gathered into groups from different labs to share our expertise and think about new ideas for our research. Program days provide a good overview of ongoing studies and projects at each group.
The Finnish Brain Research Foundation (SATS), is a member organisation of the Federation of European Neuroscience Societies (FENS), which aims to promote scientific research in the brain and nervous system and bring together researchers from different fields whose work is directed at the nervous system. SATS also organises national meetings in connection with which the SATS Board selects a highly distinguished researcher from among Finnish brain researchers and awards the "Neuroscientist of the Year" award.
In 2023, Professor Iiris Hovatta (University of Helsinki) was chosen as the winner of the prize. The prize was awarded to Hovatta in June 2023 at the Neuroscience Finland event organised by SATS. Congratulations Iiris!
Prof. Noelle L'etoile, PhD (Cell and Tissue Biology) visited our special seminar on Wed June 14th at 10-11 am at BMH1, lecture hall 2.
The talk was titled: "“Sleep is required for odor exposure to consolidate memory and remodel olfactory synapses"
The L'etoile Lab investigates how neurons perceive and transmit information both in response to novel and persistent environmental cues. We use the nematode C. elegans because its neuronal circuitry is completely described, and exhibits robust plasticity. C. elegans also allows us to use powerful cell biological, genetic, behavioral, physiological and molecular techniques to study plasticity. For example, we discovered a pathway in which nuclear translocation of a kinase and small RNAs modify chromatin, which allows environmental cues to sculpt long-term behavior. Our research may inform understanding of normal processes such as learning and memory as well as elucidate what goes awry in disease states such as addiction.
https://ctb.ucsf.edu/people
https://www.letoilelab.net/
Publications:
https://www.letoilelab.net/publications
RPU Science Day & Summer Party on May 12 2023, at University of Helsinki Great Hall and Restaurant Pörssi. SleepWell and Individrug programs are organizing the RPU Science Day this year.
RPU Science Day & Summer Party on May 12 2023, at University of Helsinki Great Hall and Restaurant Pörssi. SleepWell and Individrug programs are organizing the RPU Science Day this year.
We hope to see you there!
Tiina Paunio, MD, PhD, professor of psychiatry
Annette Horstmann, PhD, associate professor of behavioral and brain sciences
Iiris Hovatta, PhD, professor of behavioral genetics
Katri Kantojärvi, PhD, senior researcher
Hendrik Hartmann, MSc, doctoral student
Programme
13.00 - Welcome!
Eija Kalso, Chair
Professor, Faculty of Medicine, University of
Helsinki and Pain Clinic, HUS
13.05-13.50 Treating co-occurring pain and insomnia: What can cognitive-behavioural therapy
(CBT) offer?
Steven Linton
Professor of Clinical Psychology, Örebro University
13.50-14.20 Mobile-delivered therapist-assisted cognitive behavioural therapy for insomnia in Finland
Jan-Henry Stenberg
Head of IT Psychiatry and Psychosocial Treatments,
HUS
14.20-14.50 Using behavioural strategies to increase resilience to uncertainty, symptoms, and distress in chronic pain and sleep
Rikard Wicksell
Psychologist, docent, Karolinska Institute
14.50-15.00 Discussion
In Finnish:
Hybridikoulutus
(TEAMS tai Naistenklinikka)
Aika ja Paikka:
Perjantai 14.10.2022 klo 13-15
HUS Naistenklinikka, Haartmaninkatu 2,
Seth Wichman sali (rajoitettu paikkamäärä/
ennakkoilmoittautuminen) tai TEAMS-
verkkokoulutus.
Koulutuksen järjestää:
https://www.brsf.org/aivoviikko
https://www.aivosaatio.fi/aivoviikko
17:00 Tilaisuuden avaus
Professori Tiina Paunio, SleepWell ohjelmayksikön johtaja, Helsingin yliopisto
17:10 Miksi aivoterveyttä kannattaa edistää?
Professori Risto Roine, Suomen Aivot ry
Toimitusjohtaja Jenni Pajunen, Aivosäätiö
17:20 Miksi aivomme tarvitsevat unta?
Dosentti, unitutkija Tarja Stenberg, Helsingin yliopisto
17:50 Mitä jos en nuku? Unihäiriöiden taakka.
Professori, neurologian erikoislääkäri Markku Partinen
18:20 Miten nukkuisin paremmin?
Psykologi Soili Kajaste
18:50 Tilaisuuden päätös
Professori Tiina Paunio
15.00-15.10 Professor, Program Director Tiina Paunio
Opening of the symposium
15.10-15.30 Professor Katja Valli
Dreaming: what, how and why?
Katja Valli is an adjunct professor of psychology at the Department of Psychology and Speech-Language Pathology, University of Turku, Finland, and an associate professor of cognitive neuroscience at the Department of Cognitive Neuroscience and Philosophy, University of Skövde, Sweden. Her research focuses on altered states of consciousness, mainly sleep, anesthesia and dreaming, and her major works address the content and neural correlates of consciousness and dreaming, and the evolutionary function of dreaming. She has served as the president, vice-president and board member of the International Association for the Study of Dreams, and as a treasurer of the Finnish Sleep Research Society.
15.30-16.10 Professor Sophie Schwarts
Emotional processing during sleep and dreaming
MA in Biology, Ma and PhD in Psychology; PhD fellowship at UC Berkeley (Philosophy Dept. and Psychology Dept.); Postdoc training at University College London (Functional Imaging Lab). Currently, head of the Sleep and Cognition Lab and full professor at the Neuroscience Dept., Faculty of Medicine, University of Geneva, Switzerland.
Together with the collaborators in my lab, we study the role of sleep and dreaming in learning and memory processes. Our research focuses on distinct facets of neural plasticity such as perceptual and emotional learning, offline replay of neural and mental memory representations. Another interest in the lab concerns the role of the dopaminergic reward system in decision making, creativity, and dreaming. We use advanced neuroimaging approaches to assess brain functions in healthy adult volunteers, as well as in patients with neurological or psychiatric disorders.
16.10-16.50 Doctor Fransesca Siclari
Dreaming in heealthy subjects and patients with sleep disorders
Dr. Francesca Siclari graduated in medicine at the University of Geneva in 1999 and subsequently specialized in neurology and sleep medicine at the University Hospitals in Lausanne and Zürich. Between 2011 and 2014, she completed a postdoctoral fellowship at the ‘Center for Sleep and Consciousness’ in the laboratory of Giulio Tononi, where she studied the dreaming as a model of consciousness. After her return to Switzerland in 2014, she habilitated at the University of Lausanne, where she currently co-directs the Center for Investigation and Research on Sleep. Her research focuses on the scientific exploration of dreaming in both healthy subjects and patients with sleep disorders.
16.50-17.00 Break
17.00-17.40 Professor Jerry Siegel
Do animals dream?
Studies of the evolution and function of sleep.
I have been particularly interested in the functions and pathologies of REM sleep. Work in the 1970s (Allison and colleagues), concluded, from studies of the echidna, that REM sleep was not present in the early mammals, leading to the supposition that it was directly linked to advances in cognitive capability. I went to Australia to study sleep in the two “primitive” monotreme mammals, the egg laying platypus (Siegel et al., 1999) and echidna (Siegel et al., 1996). I found that they, in fact, had REM sleep. Surprisingly, the platypus has the greatest amount of REM sleep of any animal with a very high level of rapid eye movements. Subsequently, a paper on the ostrich, a primitive bird, was entitled, with reference to our 1999 paper, “Ostriches sleep like platypuses” (Lesku et al. 2011), reinforcing our conclusion that the brainstem REM sleep pattern was likely universal in early homeotherms and indeed may be the earliest form of sleep to have evolved in mammals. In June of 2018 we published a paper showing that whereas fur seals have REM sleep amounts similar to those seen in humans when they are on land, they cease having REM sleep when they are in the water, where they spend most of their lives (Lyamin et al, 2018). When they return to land they show no REM sleep “rebound.” We suggest that REM sleep is linked to bilateral nonREM sleep. Since fur seals in the water have unihemispheric nonREM sleep like dolphins, they cease having REM sleep in the water, also like dolphins. I was asked by Nature (2005) to review the evidence on sleep phylogeny and concluded that, contrary to early comparative studies, sleep duration is not inversely related to body size. A relation to body size would imply a relation to metabolic rate which has been shown to be tightly linked to body mass. Rather, sleep amount is correlated with the evolved habitual diet (not actual food consumption), with carnivores sleeping more than omnivores which in turn sleep more than herbivores. Only herbivores show an inverse relation of sleep duration to body mass, linked to the amount of time they needed to consume adequate amounts of their low calorie density food, not to brain size or metabolic rate. The study of sleep in humans living in the environment in which humans evolved, is a natural extension of this prior work. We have found (Yetish et al., 2015) that contrary to prior assumptions, hunter gatherers: 1. Do not go to sleep at sunset. 2. Sleep less, not more, than humans in most “industrial” societies. 3. Do not have midday naps or polycyclic sleep. 4. Do not regularly awaken in the middle of the night, but rather have a continuous period of nighttime sleep. 5. Have substantially different sleep amounts in winter vs. summer. 6. Do not have insomnia, in contrast to the 10-15% rates of insomnia in all industrial societies.
a. Siegel, J.M. The REM sleep-memory consolidation hypothesis. Science 294:1058-1063, 2001. PMCID: 11691984 {618}
b. Siegel, J.M. Clues to the functions of mammalian sleep. Nature 437:1264-1271, 2005 PMCID: 16251951 {846}
c. Oleg I. Lyamin, Peter O. Kosenko, Svetlana M. Korneva, Alexei L.
17.40-18.20 PhD Gianina Ungurean
A bird´s-eye view of REM sleep
Gianina Ungurean obtained a Masters of engineering in Biotechnologies at the National Institute for Applied Sciences in Lyon, France. Before starting her PhD, she studied sleep during the last year of her Masters, working on the mechanisms of sensory transmission and gating during REM sleep. For the past four years of doctoral work in the Avian Sleep group at Max Planck Institute for Ornithology in Germany (Seewiesen), she investigated different aspects of the avian sleep, with a focus on REM sleep. She employs a comparative approach to investigate the mechanisms and functions of sleep.
Uni on terveydelle tärkeää. Tämä ilmenee johdonmukaisesti väestöpohjaisissa ja laboratorioissa tehdyissä tutkimuksissa. Koska me kaikki nukumme, jokaisella yksilöllä on myös oma, selkeä käsityksensä unesta. Uni on kuitenkin monimutkainen prosessi, jonka kaikkia mekanismeja ja merkitystä ei vielä täysin tunneta.
SleepWell on Suomessa ensimmäinen kansainvälisen arvioinnin läpi käynyt yliopistollinen uneen keskittyvä tutkimusohjelma. SleepWell –tutkijat haluavat tässä tapahtumassa kertoa ymmärrettävällä tavalla unesta ja samalla purkaa erilaisia uneen liittyviä virheellisiä uskomuksia.
Kuusi puheenvuoroa:
Myytti 1: "Unentarve on aina ja kaikille sama" - Yliopistonlehtori Henna-Kaisa Wigren, HY
Myytti 2: "Uni on vain aivoja varten" - Dosentti Tarja Stenberg, HY
Myytti 3: ”Syvä uni on paras uni” – Professori Anu-Katriina Pesonen, HY
Myytti 4: ”Kipu se vain unta häiritsee” - Professori Eija Kalso, HY
Myytti 5: ”Uni paranee, kun mielikin paranee" - Professori Tiina Paunio. HY
Myytti 6: ”Unilääkkeet hoitavat unihäiriöitä" - Apulaisprofessori Tomi Rantamäki, HY
Small group discussion with experts:
Short talks by young investigators, selected based on submitted abstracts.
Target audience: Students, postdocs and faculty working on human genetic and imaging studies in psychiatric diseases, mechanisms of psychiatric diseases, including functional, pharmacological and genetic analyses in model organisms, and related fields.
Credits (NEUBM-301): Students will receive 1 ECTS from attendance + submitting a 1 page essay on the scientific content of the symposium, or 2 ECTS by attendance + essay + short talk presentation.
ONLINE REGISTRATION
Abstract submission deadline: 20.11.2020
The deadline for registration without an abstract is November 27, 2020
We hope to see you there!
Iiris Hovatta, PhD, professor of behavioral genetics
Tiina Paunio, MD, PhD, professor of psychiatry
Maija Koskinen, MSc, doctoral student
Fatma Doagu, MSc, doctoral student
Prof. Eus Van Someren was trained in physics, psychophysiology and neuropsychology and received a cum laude PhD in neurobiology from the faculty of medicine. He leads a team at the Netherlands Institute for Neuroscience, aiming to unravel brain mechanisms of chronic insomnia. He received prestigious grants including an ERC-AdG, and founded the Sleep Registry (sleepregistry.org) for rich phenotyping of over 10,000 volunteers. He (co)-authored on more than 250 peer-reviewed publications in scientific journals including NJEM, Jama, Nature Genetics, Nature Neuroscience, Lancet Psychiatry, Archives of General Psychiatry, Psychological Bulletin, Brain, Current Biology and PNAS and is widely cited (H-index 55). His informal infectious enthusiasm for a neuroscience of insomnia make him a frequently invited speaker, e.g. at TED-X.
Larry D. Sanford, PhD, is Professor and Director of the Center for Integrative Neuroscience and Inflammatory Diseases and Vice Chair for Experimental Pathology in the Pathology and Anatomy Department at Eastern Virginia Medical School, Norfolk Virginia, USA. Dr. Sanford’s primary research program is focused on using animal models to understand the role interactions between sleep, stress, and fear learning and memory play in the development of PTSD and anxiety disorders. Other work examines the role that sleep plays in mediating the effects of stress and radiation during space flight, behavioral and neural regulation of neuroinflammation, and mechanisms of neural communication
I am Professor of Sleep Medicine in the Nuffield Department of Clinical Neurosciences (NDCN), University of Oxford where I founded the Experimental & Clinical Sleep Medicine research programme in the Sleep & Circadian Research Institute (SCNi) and I am Clinical Director of the Oxford Online Programme in Sleep Medicine (https://www.ndcn.ox.ac.uk/study/graduate-students/online-programme-in-sleep-med…). I am a Fellow of Somerville College, Oxford and a Senior Research Fellow in the University Department of Psychiatry.
17.10-17.20 Break
Dr. Sara Aton received her PhD from Washington University in St .Louis, and carried out postdoctoral work at the University of Pennsylvania with Dr. Marcos Frank. Her laboratory at the University of Michigan, established in 2012, has investigated two sleep-dependent phenomena - consolidation of fear memories in the mouse hippocampus, and consolidation of experience-dependent plasticity in mouse primary visual cortex. Work from her lab, combining in vivo electrophysiology with optogenetic and pharmacogenetic manipulations of brain circuits, has established the vital role for sleep-associated network oscillations in driving both processes. Current studies being carried out in the Aton lab are characterizing how learning experiences and subsequent sleep affect basic biochemical processes in specific neuronal cell types, excitatory/inhibitory balance, and the activity and plasticity of experience-activated (i.e. engram) neurons.
Dr. Ruth Benca is Professor and Chair, Department of Psychiatry and Human Behavior at the University of California, Irvine. She received her AB at Harvard and her MD and PhD degrees from the University of Chicago. She has been a faculty member at the University of Chicago and the University of Wisconsin-Madison, where she was Associate Chair of the Psychiatry Department and Director of the UW Center for Sleep Medicine and Sleep Research. She moved to UC Irvine in 2016, where she has established a sleep medicine center providing clinical care for sleep disorders as well as promoting translational research. Her research focuses on the interface between sleep and psychiatric disorders across the lifespan, and the role of sleep and sleep disorders on Alzheimer’s disease. She has served as principal investigator for studies funded by agencies including the NIH and the DOD. Her work has spanned basic research in animal models to clinical research and clinical trials. She has authored over 150 articles, reviews and book chapters. She has served as President of the Sleep Research Society and on the Board of Directors of the American Academy of Sleep Medicine, and currently is Editor-in-chief of Current Sleep Medicine Reports and Insomnia Section Editor of UpToDate.
Dear Colleagues,
It was my pleasure to present Dr. Tarja Porkka-Heiskanen – a sleep scientist, teacher, debater, and influencer in sleep medicine – with the European Sleep Science Award 2020 during the Welcome and Opening of the Virtual Edition of our 25th Congress of the European Sleep Research Society (22 Sept 2020).
Dr. Porkka-Heiskanen received her medical degree in 1983 and her doctoral degree in 1990 from the University of Helsinki. She performed her postdoctoral studies during the 1990’s in the USA at Northwestern University and Harvard Medical school – spending two years at both.
A central revelation by Dr. Porkka-Heiskanen related to homeostatic regulation of sleep, where she identified adenosine as a key regulatory molecule during her postdoctoral research in the lab of Robert W. McCarley. This finding was published in Science in 1997 and since then, it has been one of the central reports in sleep medicine that paved the path for many other roads in modern sleep research.
Her interest in sleep research has been exceptionally wide; centered around the basic physiological mechanisms of sleep regulation, it has also extended to broader developmental dimensions –from early development to ageing, as well as to specific, gender-related aspects. She also pioneered studies on the consequences of sleep deprivation on the immune system. In 2018, Dr. PorkkaHeiskanen was awarded The Pisa Sleep Award.
She has also had central roles in many international activities, including membership in the ESRS Education and Research Committees and Board, chairing the EU Committee and establishing the ESRS Forum for Women. She has acted on the Editorial Boards of several respected international sleep journals, including the Journal of Sleep Research.
Regarding her contribution towards scientific collaboration, she has coordinated several sleepcentered international consortia and is particularly active in postgraduate education, both nationally and internationally. She established the notable Sleep School at the University of Helsinki, which recently turned into a combination of digital education and hands-on practice – all thanks to Tarja’s efforts. More recently, she pioneered future educational activity at ESRS by establishing the webbased education on basic sleep research, “eLessons”.
Tarja is still active at the University of Helsinki. She is one of our PIs for the SleepWell Research program – the first internationally evaluated research program oriented on sleep medicine at the faculty level in Finland.
As a colleague, she has been exceptionally supportive and innovative. At the same time, she is uncompromising in scientific integrity, logical thinking and scientific reasoning.
Beyond scientific activities, as some of you might know, she is an excellent dancer; she loves her garden; she is an excellent writer (and could have accomplished a career as a writer if she had wished to do so) – and, most importantly she has an unfailing sense of humor.
Again, it was my great honor – and pleasure – to introduce Dr. Tarja Porkka-Heiskanen as the recipient of the European Sleep Science Award 2020.
Thank you for your contributions towards the field of sleep science, the ESRS and your scientific collaboration and support of colleagues and young scientists.
Prof. Tiina Paunio
Laboratory of Neurotherapeutics, Drug Research Program, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, & SleepWell Research Program, Faculty of Medicine, University of Helsinki, Finland
Dr. Rantamäki and his team investigates neurobiological mechanisms underlying rapid antidepressant effects. In this seminar he will present their latest findings and recently formulated hypothesis called encoding, consolidation and renormalization in depression (ENCORE-D) that aims explaining rapid (and sustained) antidepressant effects of ketamine and related drugs beyond conventional pharmacology. The hypothesis suggests that rapid and sustained antidepressant effects rely on intrinsic homeostatic mechanisms evoked as a response to the acute pharmacological or physiologic effects (e.g. prominent synaptic potentiation) triggered by the treatment. The hypothesis incorporates elements from the synaptic homeostasis hypothesis (SHY) of sleep and suggests that the fundamental mechanisms of synaptic plasticity and sleep, particularly the homeostatic emergence of slow-wave EEG activity and the renormalization of synaptic strength, are at the center of sustaining antidepressant effects. ENCORE-D provides an interesting mechanistic framework for studying and developing rapid-acting antidepressants.
Uni on terveydelle elintärkeää. Se luo perustan niin ihmisten kuin eläinten hyvinvoinnille ja oppimiselle. Unen puutteessa mieliala kärsii, suorituskyky laskee ja pidemmän päälle fysiologisista vaikutuksista voi seurata terveysongelmia. Mutta mitä uni oikeastaan on ja miten sitä tutkitaan? Miten eläinten uni liittyy ihmisten uneen?
Helsingin yliopiston unitutkijat tarkastelevat Tiedekulmassa unta ja nukkumista eri näkökulmista. Tapahtuman juontaa Reetta Räty.
Tapahtuma on osa Tiedekulman Helsinki Health Weekiä, joka vie sinut elämäntieteiden huippuosaamisen äärelle. Osallistu tapahtumaan paikan päällä, seuraa livestriimiä tai katso tallenne! Klikkaa itsesi mukaan tapahtumaan myös Facebookissa.
Ohjelma
Mitä uni on? Kurkistus unen biologiaan
Henna-Kaisa Wigren, yliopistotutkija, unitutkimusryhmän nuorempi ryhmänjohtaja
Uni vasikan hyvinvoinnin mittana?
Laura Hänninen, kliininen opettaja, eläinlääketieteellinen tiedekunta
Ihmisen uni – mitä sillä tekee?
Liisa Kuula, kognitiotieteilijä, unitutkija
Masennuslääkkeet ja uni
Tomi Rantamäki, molekulaarisen farmakologian apulaisprofessori, farmasian tiedekunta
Laura Hänninen (@laurathanninen) on kliininen opettaja Eläinten hyvinvoinnin tutkimuskeskuksessa eläinlääketieteellisessä tiedekunnassa ja on eläinten hyvinvointiin ja käyttäytymiseen hurahtanut eläinlääkäri. “Eläinten käyttäytyminen on portti niiden mieleen, mahdollisuus saada, edes hämärästi, käsitys, mitä ne ajattelevat, mistä pitävät, mitä tuntevat”, hän sanoo. Vinkki terveyden ja hyvinvoinnin edistämiseen: “Riittävä uni! Nukun paljon, ja mielelläni.”
Tutkijatohtori Liisa Kuula (@LiisaKuula) on kognitiotieteilijä ja unitutkija Helsingin yliopistossa. Hän tutkii ihmisten nukkumista ja siihen liittyviä erilaisia ilmiöitä. Liisasta on merkillistä, että lähes kolmannes elämästämme kuluu unessa. Uni on edelleen tutkimuksellekin mysteeri, ja sen mahdista paljastuu koko ajan uutta tietoa. Tutkimusryhmänsä kanssa Liisa pyrkii löytämään syitä unen määrän, laadun ja ajoituksen vaihtelulle ja selvittämään, miten uneen voi vaikuttaa. Vinkki terveyden ja hyvinvoinnin edistämiseen: “Omaa uniterveyttään voi parantaa menemällä viikonloppuisin vartin aikaisemmin nukkumaan kuin arkisin – helppo ja halpa arvostuksen osoitus itselle.”
Tomi Rantamäki (@TomiRantamki) on molekulaarisen farmakologian apulaisprofessori farmasian tiedekunnassa ja mukana lääketieteellisen tiedekunnan SleepWell-tutkimusohjelmassa. Hän johtaa tutkimusryhmää, joka selvittää masennuslääkkeiden vaikutusten mekanismeja. Perinteisestä farmakologisesta ajattelusta poiketen tutkimusryhmä uskoo parhaiden vastausten löytyvän aivoista itsestään – siitä, miten aivot reagoivat hoitoihin. Erityisen kiehtovana Tomi pitää sitä, miten uni ja sen mekanismit liittyvät masennushoitojen toimintaan. Vinkki terveyden ja hyvinvoinnin edistämiseen: “Ole aktiivinen ja osallistuva, ja ennen kaikkea armollinen itsellesi.”
Henna-Kaisa Wigren on yliopistotutkija SleepWell-tutkimusohjelmassa ja unitutkimusryhmän nuorempi ryhmänjohtaja. Henna-Kaisa väittää, että aivojen toimintaa on mahdotonta ymmärtää tutkimalla pelkästään valvetta. Sen sijaan pitää ymmärtää, miksi vireystilat vuorottelevat ja miten aivojen tiedonkäsittely muuttuu unen ja valveen välillä. Erityisesti häntä kiinnostaa, miksi uni on elintärkeää ja miksi unta tai unenkaltaista tilaa esiintyy kaikilla lajeilla. Vinkki terveyden ja hyvinvoinnin edistämiseen: “Kun tekee valveilla ollessaan intensiivisesti aivoja haastavia asioita, jotka tuottavat mielihyvää, tulee samalla vahvistaneeksi luonnollisen unipaineen kertymistä ja silloin uni on yöllä syvempää, pidempää ja palauttavampaa.”
Paikka: Biomedicum Helsinki 1, luentosali 1
Osoite: Meilahti, Haartmaninkatu 8, Helsinki
Järjestäjä: Biomedicum Helsinki -säätiö, Helsingin ja Uudenmaan sairaanhoitopiiri ja HY lääketieteellinen tdk
17.00-17.30 Professori Iiris Hovatta, HY
Stressin fysiologiaa
17.30-18.00 Akatemiaprofessori Katri Räikkönen-Talvitie, HY
Elämän alkuvaiheen stressi
18.00-18.30 Professori, ylilääkäri Tiina Paunio, HY, HUS
Kuinka hallita stressiä?
18.30-19.00 Yleisökysymykset ja keskustelu
Kahvitarjoilu klo 16.00
Vapaa pääsy. Tervetuloa!
The symposium will include:
Short talks by young investigators, selected based on submitted abstracts.
Target audience: Students, postdocs and faculty working on human genetic and imaging studies in psychiatric diseases, mechanisms of psychiatric diseases, including functional, pharmacological and genetic analyses in model organisms, and related fields.
Credits (NEUBM-301): Students will receive 1 ECTS from attendance + submitting a 1 page essay on the scientific content of the symposium, or 2 ECTS by attendance + poster/oral presentation + essay.
We hope to see you there!
Iiris Hovatta, PhD, professor of behavioral genetics
Tiina Paunio, MD, PhD, professor of psychiatry
Mikaela Laine, MSc, doctoral student
Fatma Doagu, MSc, doctoral student
Remote Christmas party on 17th December in zoom
During pandemic program got it´s first research day at Hanasaari