Sleep & stress in health and in transition from acute to chronic diseases - from  neurobiological mechanisms to novel treatment approaches (SLEEPWELL)

SLEEPWELL is a multidisciplinary, translational and future-oriented research network bringing together expertise from clinical medicine, psychology, genetics, neurobiology and neuropharmacology. Researchers from different stages of career are assembled around the core scientific idea: the importance of sleep in resilience to stress and in recovery processes.

We work from bedside to bench, and back to bedside to extend our understanding on the role of sleep in plasticity processes during the different stages of development, with a particular focus on youth and young adults. Our research is based on the hypothesis that disturbed sleep has a central role in developmental processes and in the  transition of an acute illness to a chronic disease such as depression, anxiety disorder, or chronic pain. The methods of research extend from population-based and clinical samples to experimental research and animal models.

Our ultimate goal is to develop evidence-based novel interventions to prevent the disease development to chronic conditions via promoting brain plasticity by tools such as face-to-face and internet-based psychosocial treatments, neurostimulatory and novel pharmacological approaches, as well as enhancement of slow wave activity by targeted stimulation of brain.