People

Principal investigator

Dr. Timo is the PI of the PREP research team. He did already his M.Sc. and Ph.D. theses on PREP (in the University of Kuopio), so Timo has strong background on PREP research. Post doc periods in Helsinki, Belgium and USA teached Timo how to use different preclinical models of neurodegenerative diseases from protein level to animal models. His passion is to find a disease-modifying drug for currently unstoppable neurodegenerative diseases like Alzheimer's and Parkinson's disease.

See Timo's profile in university's research portal

Docent, senior researcher

Dr. Erik Wallen is the leader of PREP lab Medicinal Chemistry, and has 20 years experience on different medicinal chemistry projects. Erik was also involved with earlier PREP inhibitor development in University of Kuopio, so he really knows what PREP and PREP inhibitor compounds are about.

Erik's profile in university's research portal

Post-doc researcher

Dr. Johanna Uhari-Väänänen is the latest member of PREP lab. She did her PhD on alcohol addiction project in University of Helsinki, and will be now working with some novel models in neurodegenerative disases.

See Johanna's researcher page in researcher portal here.

 

Post-doctoral researcher

Dr. Hengjing Cui joined to PREP lab at 2019 as a visiting post-doctoral researcher. She got her PhD in pharmacology at 2015 from Shangai Jiao Tong University, and will be now visiting for a year in PREP lab. Her project will clarify further the role of PREP in autophagy and intracellular signalling.

PhD student

M.Sc. Tommi Kilpeläinen started as a PhD student at November 2016, and before that he performed his M.Sc. project in PREP lab and was working for a while as a research assistant. His project focuses on clarifying the effects of PREP inhibitor structures on protein aggregation, and Tommi works as a multitalent between medicinal chemistry and pharmacology.

Tommi's profile in university's research portal

Post-doctoral researcher

Francesca has strong background in animal models of neurodegenerative diseases, and her main responsibility will be in vivo work in the Business Finland TUTLI project.

See Francesca's profile in UH research portal here.

PhD student

M.Sc. Henri Pätsi is the most recent PhD student in PREP lab. He already made M.Sc. thesis in PREP lab at the beginning of 2018 and has worked as a research assistant after that prior to starting his PhD journey. Henri's project is to find novel PREP inhibitor structures.

PhD student

Tony is currently the most recent member of PREP lab as he started working for his PhD in Business Finland project at the beginning of 2019.

Post-doctoral researcher

Mikael Jumppanen, PhD, is an experienced medicinal chemist who gained his PhD under the supervision of Prof. Jari Yli-Kauhaluoma in the huge 3iRegeneration project. Mikael further streghtens the MedChem team of PREP lab.

See Mikael's research profile here.

Commercial champion

M.Sc. Samuli Auno is a commercial champion in the Business Finland TUTLI project. His responsibilities in  PREP lab is to take care of commercialization activities of TUTLI project together with Helsinki Innovation Services. Additionally, he conducts in vitro research activities for the project and handles social media accounts during his stay.

Domestic collaborations

Docent Henri Huttunen
Neuroscience Center, University of Helsinki

Dr. Maija Lahtela-Kakkonen
School of Pharmacy, University of Eastern Finland

Dr. Tapani Viitala
Division of Pharmaceutical Biosciences, University of Helsinki

Prof. Kai Kaarniranta
School of Medicine, University of Eastern Finland

Prof. Jukka Westermarck
Faculty of Medicine, University of Turku

Prof. Arto Urtti
Division of Pharmaceutical Biosciences, University of Helsinki

MD, PhD Antti Huotarinen
Kuopio University Hospital

Dr. Anu Airaksinen
Laboratory of Radiochemistry, University of Helsinki

Prof. Dan Lindholm
Department of Biochemistry and Developmental Biology, University of Helsinki

International collaboration

Dr. Stephen Haggarty
Department of Neurology, Harvard Medical School, USA

Dr. Anna Erlandsson
Department of Public Health and Caring Sciences, Uppsala University, Sweden

Prof. Kathleen Maguire-Zeiss
Department of Neuroscience, Georgetown University Medical Center, Washington DC, USA

Dr. Brandon Harvey
National Institute of Drug Abuse (NIDA), Baltimore, USA

Prof. Anne-Marie Lambeir
Laboratory of Biochemical Medicine, University of Antwerp, Belgium

Prof. Pieter van der Veken
Department of Pharmaceutical Sciences, University of Antwerp, Belgium

Prof. Poul Henning Jensen
Institute for Biomedicine, Aarhus University, Denmark

 

We have been lucky to have several exceptional people in our lab:

Dr. Ulrika Julku 2014-2020 - PhD student and a post-doctoral researcher, now as a post-doctoral researcher in Uppsala University, Sweden.

Susanna Norrbacka 2014-2020 - lab technican, now as a lab analyst in VTT, Finland.

Dr. Reinis Svarcbahs 2013-2019 - PhD student and a post-doctoral researcher, now as a post-doctoral researcher in Shenzhen University Hospital, China

Dr. Maria Jäntti 2017-2019 - now as a post-doctoral researhcer in National Institute of Drug Abuse (NIDA), Baltimore, MD; USA

Dr. Teppo Leino 1-9/2018 - now as a post-doctoral researcher in Department of Chemistry, University of Jyväskylä

Research assistant Titvi Räisänen, 6-8/2019

Research assistant Kalle Manninen, 6-8/2018

M.Sc. Lydia Zouzoula, Aristotle University of Thessaloniki, ERASMUS internship 1-5/2019

M.Sc. Anna Kalinina, State University of Moscow, Exchange student 1-6/2018

M.Sc. Tiina Huovila, M.Sc. student 11/2016-4/2017

M.Sc. Marta Chavero, University of Barcelona, ERASMUS internship 8-12/2017

Dr. Mari Savolainen, PhD student and post doctoral researcher, 2/2011-9/2016. Did 1-year post doc-period in Prof. Jeffrey Kordower's lab (Rush University, Chicago, USA), now a medical scientific partner in UCB.

M.Sc. Sigrid De Lepeleire, University of Antwerp, Belgium, ERASMUS internship 2-6/2016

M.Sc. Saija Tiilikainen, M.Sc. student and lab technician 12/2014-8/2015

B.Sc. Patrycja Pabis, Jagellonian University, Krakow, Poland – ERASMUS internship 1/2015-5/2015, and PhD student 1/2017-9/2017.

M.Sc. Ilari Korhonen – a research assistant 6-8/2014

M.Sc. Najda Selak, University of Zagreb, Croatia – ERASMUS internship 1/2014-5/2014

M.Sc. Sauli Pätsi – Pro Gradu project 1/2012-6/2012

M.Sc Lana Dokleja, University of Zagreb, Croatia – ERASMUS internship and technical assistant 1/2011-8/2011