Publications

• Panula, P. and Nuutinen, S. The histaminergic network in the brain: basic organization and role in disease. Nature Reviews Neuroscience 14: 472-487, 2013.
• Reimer, M.M., Norris, A., Ohnmacht, J., Patani, R., Zhong, Z., Dias, T.B., Kuscha, V., Scott, A.L., Chen, Y.C., Rozov, S., Frazer, S.L., Wyatt, C., Higashijima, S.I., Patton, E.E., Panula, P., Chandran, S., Becker, T., Becker, C.G..: Dopamine from the Brain Promotes Spinal Motor Neuron Generation during Development and Adult Regeneration. Devel. Cell doi: 10.1016/j.devcel.2013.04.012, 2013
• Panula, P., Sundvik, M. and Karlstedt, K.: The role of histamine in brain development. Trends in Neurosciences 37:159-68, 2014.
• Vanhanen, J., Kinnunen, M., Nuutinen, S. and Panula, P.: Histamine H3 receptor antagonist JNJ-39220675 modulates locomotor responses but not place conditioning by dopaminergic drugs. Psychopharmacology 232: 1143-1153, 2015.
• Panula, P., Chazot, P.D., Cowart, M., Gutzmer, R., Leurs, L., Liu, W.L.S., Stark, H., Thurmond, R., Haas, H.L.: International Union of Pharmacology. XCVIII. Histamine receptors. Pharmacol. Rev. 67: 601-655, 2015.
• Chen YC, Harrison PW, Kotrschal A, Kolm N, Mank JE, Panula P. Expression change in Angiopoietin-1 underlies change in relative brain size in fish. Proc Biol Sci. 2015 Jul 7;282. doi: 10.1098/rspb.2015.0872.
• Nuutinen S, Mäki T, Rozov S, Bäckström P, Hyytiä P, Piepponen P, Panula P. Histamine H3 receptor antagonist decreases cue-induced alcohol reinstatement in mice. Neuropharmacology. 2015. pii: S0028-3908(15)00264-6. doi: 10.1016/j.neuropharm.2015.06.006.
• Keatinge M, Bui H, Menke A, Chen YC, Sokol AM, Bai Q, Ellett F, Da Costa M, Burke D, Gegg M, Trollope L, Payne T, McTighe A, Mortiboys H, de Jager S, Nuthhall H, Kuo MS, Fleming A, Schapira AH, Renshaw SA, Highley JR, Chacinska A, Panula P, Burton EA, O'Neill MJ, Bandmann O. Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death. Hum Mol Genet. 24:6640-6652, 2015. doi: 10.1093/hmg/ddv369
• Nuutinen S, Panula P, Salminen O. Different Hypothalamic Nicotinic α7 Receptor Expression and Response to Low Nicotine Dose in Alcohol-Preferring and Alcohol-Avoiding Rats. Alcohol Clin Exp Res. 40:329-34, 2016. doi: 10.1111/acer.12960.
• Kononoff Vanhanen J, Nuutinen S, Tuominen M, Panula P. Histamine H3 Receptor Regulates Sensorimotor Gating and Dopaminergic Signaling in the Striatum. J Pharmacol Exp Ther. 357:264-72, 2016. doi: 10.1124/jpet.115.230771
• Chen YC, Semenova S, Rozov S, Sundvik M, Bonkowsky JL, Panula P. A novel developmental role for dopaminergic signaling to specify hypothalamicneurotransmitter identity. J Biol Chem. 291(42):21880-21892, 2016 pii: jbc.M115.697466.
• Abdurakhmanova S, Chary K, Kettunen M, Sierra A, Panula P. Behavioral and stereological characterization of Hdc KO mice: relation to Tourette syndrome. J Comp Neurol. 2017 doi: 10.1002/cne.24279. [Epub ahead of print]
• Semenova S, Rozov S, Panula P. Distribution, properties, and inhibitor sensitivity of zebrafish catechol-O-methyl transferases (COMT). Biochem Pharmacol. 145:147-157, 2017. doi: 10.1016/j.bcp.2017.08.017. [Epub ahead of print]
• Baronio D, Puttonen HAJ, Sundvik M, Semenova S, Lehtonen E, Panula P. Embryonic exposure to valproic acid affects the histaminergic system and the social behaviour of adult zebrafish (Danio rerio). Br J Pharmacol. 2018;175:797-809. doi: 10.1111/bph.14124
• Puttonen HAJ, Sundvik M, Semenova S, Shirai Y, Chen YC, Panula. Knockout of histamine receptor H3 alters adaptation to sudden darkness and monoamine levels in the zebrafish. Acta Physiol (Oxf). 2018;222. doi: 10.1111/apha.12981

Recent publications