Principal investigator: Mikko Frilander

The key focus of our lab is pre-mRNA splicing and it's regulation. Additionally we investigate genomics, tanscriptomics and pre-mRNA processing with various non-model organisms. Our research is focused on the regulatory aspects of the U12-type spliceosome and the molecular mechanisms of human diseases with defects in the minor spliceosome components. Additionally, we are also studying mechanism of assembly and the architecture of this spliceosome.

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CON­TACT

Research director Mikko Frilander
Institute of Biotechnology
PO Box 56 (Viikinkaari 5)
FI-00014 University of Helsinki
FINLAND

Biocenter 2, Room 4025
Phone: +358 2941 59509, +358 50 448 4567
E-mail: mikko.frilander@helsinki.fi

Schematic representation of the function of the RNPC3 gene product, U11/U12-65K protein, in RNA splicing.