Single cell transcriptomics symposium 2017

DPBM-121 (1 ECTS)

27 September 2017, 9:00-17:00

Biomedicum Helsinki 1, Lecture Hall 2

9:00-9:05 Welcoming words (Päivi Saavalainen)

Session I: Cellular and disease heterogeneity (Chair: Päivi Saavalainen)

9:05-9:50 Gioele La Manno (Karolinska Institute, Sweden): A single cell atlas of brain development

9:50-10:10 Anna Vähärautio (University of Helsinki): Single-cell characterisation of drivers in HGS-ovarian cancer tumors

10:10-10:30 Pirkko Mattila (University of Helsinki): Utilizing single cell RNAseq as well as bulk RNAseq data to study AML –patients

10:30-10:55 Coffee break with sponsor exhibition

Session II: Cell differentiation and immunology (Chair: Anna Vähä-Rautio)

10:55-11:20 Juha Kere (Karolinska Institute, Sweden): Transcriptional control of human embryo genome activation

11:20-11:40 Henna Tyynismaa (University of Helsinki): Uncovering disease pathways in patient-specific motor neurons using single cell RNAseq

11:40-12:00 Tapio Lönnberg (University of Turku): Resolving T cell fates using single-cell RNA-seq

12:00-13:10 Lunch seminar with sponsor presentations (free sandwich lunch for 120 quickest participants):

Seminar room 1-2 (60 seats): 12:00/10x genomics  - 12:15/Dolomite-Bio – 12:30/Bio-Rad&Illumina – 12:45/AH Diagnostics -13:00-13:10 break

Seminar room 3 (60 seats): 12:00-12:10/break – 12:10/Bio-Rad&Illumina   – 12:25/AH Diagnostics – 12:40/10x genomics  - 12:55-13:10/Dolomite-Bio

Session III: Single-cell method development (Chair: Outi Monni)

13:10-13:30 Päivi Saavalainen (University of Helsinki): Drop-seq protocols in autoimmune research

13:30-13:50 Marc Wadsworth (MIT, US): Seq-Well: A Portable, Low-Cost Platform for Single-Cell RNA-Seq of Low-Input Clinical Samples

13:50 -14:35 Assaf Weiner (Weizmann Institute, Israel): From single cell RNA-seq to bedside: personalized characterization of pathways and mechanism of multiple myeloma onset

14:35 -15:00 Coffee break with sponsor exhibition

15:00 -15:20 Mantas Survila (University of Helsinki): InDrop single cell mRNA sequencing uncovers neuronal development and diversity in the mouse brainstem

Session IV: Computational analysis of single cell data (Chair: Eija Korpelainen)

15:20-16:05 Tallulah Andrews (Welcome Trust Sanger Institute, UK): Comparing cell-type transcriptomes across species and disease states

16:05-16:50 Christopher Yau (University of Birmingham, UK): Probabilistic models for pseudotime estimation in single cells and populations

16:50 - 17:00 Closing the symposium

Registration has closed at 15th September and the seats are full now. If you need to cancel your participance, please inform Late registrants, request from the same e-mail for possible cancellations/free seats.

Organizers/course sponsors: Doctoral Program in Biomedicine (DPBM), Päivi Saavalainen, Anna Vähärautio and Outi Monni, 10x Genomics, Dolomite-Bio, Bio-Rad, Illumina, AH Diagnostics, Lexogen