Haartmaninkatu 8 (PO Box 63)
00014 University of Helsinki
Phone: +358 2941 25555
E-mail: liisa.kauppi@helsinki.fi
My research focuses on DNA damage repair, especially homologous recombination (HR) repair, in high-grade serous ovarian cancer (HGSOC). In our lab, we have established an immunofluorescence-based assay to detect HR deficiency in HGSOC tumor cells. By utilizing this assay, my aim is to find a way to (re-)sensitize cancer cells to chemotherapy by manipulating HR repair pathway.
E-mail: sanna.pikkusaari@helsinki.fi
LINE-1 are transposable elements that comprise approximately 17% of human DNA. Even though silent in normal cells, LINE-1s are transcriptionally active in different types of cancer, often resulting in de novo insertions and therefore conducting to genomic instability. I am interested to understand the genomic evolution of LINE-1 activity in high-grade serous ovarian cancer.
E-mail: fatih.genc@helsinki.fi
My project seeks to determine the composition of the ovarian cancer microbioma (oncobiome) in tissue samples with low and high DNA damage. The end result is expected to provide a general idea about the impact of the omcobiome on the behaviour of the tumor (resistance, aggressiveness, responsiveness to treatment).
The goal of my project is to understand the temporal location of the DNA damage (% in S phase), the differences in the tumour microenvironment (TME) between HR-deficient and HR-proficient tumours and propose avenues for alternative treatment strategies.
E-mail: minna.eriksson@helsinki.fi
Phone: 0504489442
Technical Assistant
Undergraduate student
Miia Kaistamaa, MD
Kul Shrestha, PhD
Manuela Tumiati, PhD
Nanna Sarvilinna, PhD
Imrul Faisal, PhD
Linlin Zhang, MD, PhD
Susanna Jonkka, MSc
Denis Dermadi Bebek, PhD
Vanessa Keser, ERASMUS student
Venkatram Yellapragada, MSc
Martyna Salciute, BSc
Elli Aska, PhD
Jasmin Grönman, MSc
Juha Matilainen, PhD
Barun Pradhan, post-doc
Henrik Talsi, summer student
Oona Mehtälä, summer student
Maarit Hakkarainen, lab technician
Taina Turunen, lab technician
Minna Tuominen, lab manager
Saundarya Shah, lab manager